NG-nitro-L-arginine - Moligand™, 10 mM in DMSO , CAS No.2149-70-4

CAS: 2149-70-4 Cat. No.: N1495332 Peso molecular: 219.2 Beilstein Registry Number: 1728914 Número EC: 218-418-9

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

NG-nitro-L-arginine (Nω-nitro-L-arginine) is a NO Synthase inhibitor, with K i s of 0.61 μM ( nNOS ), 4.28 μM ( iNOS ), 0.72 μM ( eNOS ) respectively. NG-nitro-L-arginine inhibits endothelium-derived relaxing factor ( EDRF ) formation and release. NG-nitro-L-arginine inhibits portal-systemic shunting in portal-hypertensive rats, and increases blood pressure .

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Nombres e identificadores

• Isómeros SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N[N+](=O)[O-]
• WGK Alemania: 3
• RTECS: RM2982100
• Peso molecular: 219.2
• Beilstein: 1728914
• Reaxy-Rn: 28511352
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28511352&ln=

Propiedades químicas y físicas

• Rotación específica [α]: [a]20/D +23.0 to +31.0 deg(C=2,2mol/L HCl)
• Punto de fusión (°C): 257°C

Referencias

1. Ji-Hong Chen, Qian Zhang, Yuanjie Yu, Kongling Li, Hong Liao, Longying Jiang, Lu Hong, Xiaohui Du, Xinghai Hu, Sifeng Chen, Sheng Yin, Qingmin Gao, Xiangdong Yin, Hesheng Luo, Jan D. Huizinga.  (2013)  Neurogenic and Myogenic Properties of Pan-Colonic Motor Patterns and Their Spatiotemporal Organization in Rats.  PLoS One,  8  (4): (e60474).  [PMID:23577116] [10.1371/journal.pone.0060474]

2. Lili Zhao, Shuhua Zhu, Jie Zhou.  (2012)  A novel amperometric nitric oxide sensor based on imprinted microenvironments for controlling metal coordination.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2012.05.035]