Nicotinic acid mononucleotide - ≥95% , CAS No.321-02-8

CAS: 321-02-8 Cat. No.: N487022 Peso molecular: 335.2

GRADE & PURITY ≥95%

Synonyms

3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium | nicotinic acid mononucleotide | NaMN | [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate | nicotinate mononucleotide | A-Nicotinic Acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Nicotinic acid mononucleotide (NaMN) is formed from nicotinic acid 5-phosphoribosyl-1-pyrophosphate (PRPP) in the Preiss-Handler pathway in the presence of enzyme phosphoribosyltransferase (NaPRT).Nicotinic acid mononucleotide has been used as a substrate for NMN/NaMN adenylyltransferase (NMNAT) during nicotinamide adenine dinucleotide (NAD) biosynthesis.

Specifications

Sinónimos

3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium | nicotinic acid mononucleotide | NaMN | [(2R, 3S, 4R, 5R)-5-(3-carboxypyridin-1-ium-1-yl)-3, 4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate | nicotinate mononucleotide | A-Nicotinic Acid

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

Nicotinic acid mononucleotide (NaMN) may be used to study the relationship between the phosphate-responsive signaling (PHO) pathway and nicotine adenine dinucleotide (NAD(+)) metabolism in yeast. Nicotinate mononucleotide is a substrate for NMN/NaMN adeny

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504763523
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504763523
• Sonrisas canónicas: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)O
• IUPAC Name: [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
• InChIKey: JOUIQRNQJGXQDC-ZYUZMQFOSA-N
• INCHI: 1S/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/m1/s1
• Isómeros SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)O
• Peso molecular: 335.2
• Reaxy-Rn: 57922182
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=57922182&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Pyridine nucleotides
      • Subclass Nicotinic acid nucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Pyridine nucleotides
• Subclass: Nicotinic acid nucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Nicotinic acid nucleotides
• Alternative Parents: Pentose phosphates Glycosylamines Monosaccharide phosphates Pyridinecarboxylic acids Alkaloids and derivatives Monoalkyl phosphates Pyridinium derivatives Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Secondary alcohols 1,2-diols Carboxylic acid salts Oxacyclic compounds Azacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Organic zwitterions Organopnictogen compounds Organic salts Hydrocarbon derivatives Organic oxides Organonitrogen compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Nicotinic-acid-nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - Monosaccharide phosphate - Pentose monosaccharide - Pyridine carboxylic acid - Alkaloid or derivatives - Pyridine carboxylic acid or derivatives - Monoalkyl phosphate - Monosaccharide - Organic phosphoric acid derivative - Phosphoric acid ester - Pyridine - Pyridinium - Alkyl phosphate - Vinylogous amide - Tetrahydrofuran - Heteroaromatic compound - Carboxylic acid salt - Secondary alcohol - 1,2-diol - Azacycle - Oxacycle - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Organic salt - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Alcohol - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic zwitterion - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as nicotinic acid nucleotides. These are pyridine nucleotides, in which the pyridine base is nicotinic acid or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y