Nimesulide - Moligand™, 10mM in DMSO , Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2, CAS No.51803-78-2, Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2

CAS: 51803-78-2 Cat. No.: N407977 Fórmula: C13H12N2O5S Peso molecular: 308.31 Número EC: 257-431-4
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
N-​(4-​nitro-​2-​phenoxyphenyl)​-methanesulfonamide
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
Alemania (EU)*
Price
Qty
1ml
N407977-1ml
1 Disponible
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106,90US$

154,90US$
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Nimesulide is a relativelyCOX-2selective inhibitor withIC50of 26 μM.
In vitro


In vivo


Cell Data

cell lines:HepG2 cells

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
N-​(4-​nitro-​2-​phenoxyphenyl)​-methanesulfonamide
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Mecanismo de acción
Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2
Nombres e identificadores
Isómeros SMILES
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
WGK Alemania
3
RTECS
PB0970000
Peso molecular
308.31
Reaxy-Rn
2421175
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2421175&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
SLC6A19 Tchem Sodium-dependent neutral amino acid transporter B(0)AT1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (8 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSolubility (25°C) In vitro DMSO: 66 mg/mL (198.11 mM); Ethanol: -1 mg/mL  
Punto de fusión (°C)150 °C
Preguntas frecuentes y artículos
Citations of This Product
Calculadoras de soluciones
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