≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Product description：
Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. Nisoxetine hydrochloride is an antidepressant and local anesthetic, it can block voltage-gated sodium channels.
Application：
Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.
Potent and selective norepinephrine reuptake (NET) inhibitor (K i values are 0.46, 158 and 505 nM for NET, SERT and DAT, respectively).
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Desiccated
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as anisoles. These are organic compounds containing a methoxybenzene or a derivative thereof.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Wei Dong, Qin Zhou, Wangqiang Shen, Le Yang, Peng Jin, Xing Lu, Yongfu Lian. (2023) The Various Packing Structures of Tb@C82 (I, II) Isomers in Their Cocrystals with Ni(OEP). Nanomaterials, 13 (6):(994). [PMID:36985888][10.3390/nano13060994]
2.Xin Song, Jiangle An, Chao He, Jukai Zhou, Yuanting Xu, Haifeng Ji, Li Yang, Jiarui Yin, Weifeng Zhao, Changsheng Zhao. (2019) A bioinspired strategy towards super-adsorbent hydrogel spheres via self-sacrificing micro-reactors for robust wastewater remediation. Journal of Materials Chemistry A, 7 (37):(21386-21403). [PMID:][10.1039/C9TA05550A]
3.Sun Fu-Hua, Dong Jinfeng, Tang Huaichao, Zhuang
Hua-Lu, Li Jing-Feng. (2018) ZnO-Nanoparticle-Dispersed Cu11.5Ni0.5Sb4S13−δ Tetrahedrite Composites with Enhanced Thermoelectric Performance. JOURNAL OF ELECTRONIC MATERIALS, 48 (4):(1840-1845). [PMID:][10.1007/s11664-018-06839-3]
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