Determine the necessary mass, volume, or concentration for preparing a solution.
NITD-688 - ≥99% , CAS No.2407227-31-8
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items
Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV)
In Vitro
NITD-688 shows antiviral activity against all four serotypes of dengue virus (DENV), with EC 50 values of 8 to 38 nM. NITD-688 shows antiviral activity against DENV-2 infected PBMCs, with an EC 50 value of 0.94 nM. NITD-688 directly binds to wild-type but not mutant NS4B protein. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
NITD-688 (30 mg/kg, oral gavage, twice daily for 3 days) demonstrates excellent antiviral efficacy in infected AG129 mice . NITD-688 (15-300 mg/kg, oral gavage, per day for 7 days) is well tolerated in rats and dogs (toxicology studies) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Infected AG129 mice Dosage: 30 mg/kg Administration: Oral gavage, twice daily for 3 days Result: Resulted in a 1.16-log reduction in viremia.
Form:Solid
IC50& Target:NS4B
Specifications
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV).
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥99%
Nombres e identificadores
| Isómeros SMILES | CC1(CC2=C(CN1CC3CCCCC3)C(=C(S2)NC(=O)CC4=CC=C(C=C4)S(=O)(=O)N)C#N)C |
|---|---|
| PubChem CID | 146279852 |
| Peso molecular | 500.68 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 100 mg/mL (199.73 mM; ultrasonic and warming and heat to 60°C) |
|---|
Calculadoras de soluciones
Reseñas
Reseñas de cliente
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.