NQTrp - ≥95% , CAS No.185351-19-3

CAS: 185351-19-3 Cat. No.: N286859 Peso molecular: 360.36 Número EC: 808-550-0
Disponible para pedir
GRADE & PURITY ≥95%
Synonyms
NQTrp, >=98% (HPLC) | DTXSID30717912 | (1,4-dioxo-1,4-dihydronaphthalen-2-yl)-L-tryptophan | 1,4-naphthoquinon-2-yl-l-tryptophan | AKOS027470177 | nqtrp | HY-19738 | (2S)-2-[(1,4-DIOXONAPHTHALEN-2-YL)AMINO]-3-(1H-INDOL-3-YL)PROPANOIC ACID | MS-25694 | N-(
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
N286859-5mg
2
126,90US$
10mg
N286859-10mg
2
185,90US$
25mg
N286859-25mg
2
417,90US$
50mg
N286859-50mg
2
741,90US$
100mg
N286859-100mg
2
1.334,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
NQTrp, >=98% (HPLC) | DTXSID30717912 | (1, 4-dioxo-1, 4-dihydronaphthalen-2-yl)-L-tryptophan | 1, 4-naphthoquinon-2-yl-l-tryptophan | AKOS027470177 | nqtrp | HY-19738 | (2S)-2-[(1, 4-DIOXONAPHTHALEN-2-YL)AMINO]-3-(1H-INDOL-3-YL)PROPANOIC ACID | MS-25694 | N-(
Especificaciones y pureza
≥95%
Mecanismos bioquímicos y fisiológicos
Potent inhibitor of Aβoligomer and fibril formation (IC50= 50 nM for formation of fibrils from Aβ1-42). Reduces cytotoxicity of Aβoligomers and increases cell viability in neuronal cells. Significantly extends lifespan of Drosophila expressing human Aβ1-4
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥95%
Nombres e identificadores
Pubchem Sid504771422
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504771422
Sonrisas canónicasC1=CC=C2C(=C1)C(=O)C=C(C2=O)NC(CC3=CNC4=CC=CC=C43)C(=O)O
IUPAC Name(2S)-2-[(1,4-dioxonaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid
InChIKeyDZZUYZXINNHEGM-SFHVURJKSA-N
INCHI1S/C21H16N2O4/c24-19-10-17(20(25)15-7-2-1-6-14(15)19)23-18(21(26)27)9-12-11-22-16-8-4-3-5-13(12)16/h1-8,10-11,18,22-23H,9H2,(H,26,27)/t18-/m0/s1
Isómeros SMILES C1=CC=C2C(=C1)C(=O)C=C(C2=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O
Peso molecular 360.36
Reaxy-Rn 25282926
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25282926&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseIndoles and derivatives
SubclassIndolyl carboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentIndolyl carboxylic acids and derivatives
Alternative Parents Naphthoquinones  3-alkylindoles  L-alpha-amino acids  Quinones  Aryl ketones  Aralkylamines  Substituted pyrroles  Vinylogous amides  Heteroaromatic compounds  Monocarboxylic acids and derivatives  Enamines  Dialkylamines  Carboxylic acids  Azacyclic compounds  Hydrocarbon derivatives  Organic oxides  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Indolyl carboxylic acid derivative - Naphthoquinone - Alpha-amino acid - Alpha-amino acid or derivatives - L-alpha-amino acid - Naphthalene - 3-alkylindole - Indole - Quinone - Aryl ketone - Aralkylamine - Substituted pyrrole - Benzenoid - Vinylogous amide - Pyrrole - Heteroaromatic compound - Ketone - Carboxylic acid derivative - Carboxylic acid - Secondary aliphatic amine - Enamine - Azacycle - Monocarboxylic acid or derivatives - Amine - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as indolyl carboxylic acids and derivatives. These are compounds containing a carboxylic acid chain (of at least 2 carbon atoms) linked to an indole ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus vulgaris (5823 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeFechaArticulo
J2214595Certificate of AnalysisJul 10, 2025 N286859
J2214596Certificate of AnalysisJul 10, 2025 N286859
J2214597Certificate of AnalysisJul 10, 2025 N286859
J2214598Certificate of AnalysisJul 10, 2025 N286859
J2214600Certificate of AnalysisJul 10, 2025 N286859
K2413039Certificate of AnalysisJun 15, 2022 N286859
Propiedades químicas y físicas
SolubilidadSolvent:DMSO, Max Conc. mg/mL: 36.04, Max Conc. mM: 100
Peso molecular360.400 g/mol
XLogP33.400
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass360.111 Da
Monoisotopic Mass360.111 Da
Topological Polar Surface Area99.300 Ų
Heavy Atom Count27
Formal Charge0
Complexity659.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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