Nuciferine - analytical standard , CAS No.475-83-2

CAS: 475-83-2 Cat. No.: N115702 Peso molecular: 295.376 Número EC: 842-235-9
Disponible para pedir
GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
Synonyms
D-(-)-NUCIFERINE | (-)-Nucipherine | Q7067904 | 1,2-Dimethoxy-6abeta-aporphine | l-Nuciferine | s3821 | VLT 049 | MFCD01664592 | BS-42200 | HY-N0049 | (R)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | 6a-beta-APORPHINE, 1,2-DIMETH
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
25mg
N115702-25mg
5

147,90US$

274,90US$
Guardar 127,00 US$ (46.20%)
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Why this grade

analytical standard Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
D-(-)-NUCIFERINE | (-)-Nucipherine | Q7067904 | 1, 2-Dimethoxy-6abeta-aporphine | l-Nuciferine | s3821 | VLT 049 | MFCD01664592 | BS-42200 | HY-N0049 | (R)-1, 2-dimethoxy-6-methyl-5, 6, 6a, 7-tetrahydro-4H-dibenzo[de, g]quinoline | 6a-beta-APORPHINE, 1, 2-DIMETH
Especificaciones y pureza
analytical standard
Condiciones de almacenamiento de almacenamiento
Room temperature
Enviado en
Normal
Grado
Analytical standard
Nombres e identificadores
Sonrisas canónicasCN1CCC2=CC(=C(C3=C2C1CC4=CC=CC=C43)OC)OC
IUPAC Name(6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
InChIKeyORJVQPIHKOARKV-OAHLLOKOSA-N
INCHI1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1
Isómeros SMILES CN1CCC2=CC(=C(C3=C2[C@H]1CC4=CC=CC=C43)OC)OC
Peso molecular 295.376
Reaxy-Rn 91203
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=91203&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassAlkaloids and derivatives
ClaseAporphines
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentAporphines
Alternative Parents Phenanthrenes and derivatives  Benzoquinolines  Tetrahydroisoquinolines  Naphthalenes  Anisoles  Aralkylamines  Alkyl aryl ethers  Trialkylamines  Azacyclic compounds  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Aporphine - Benzoquinoline - Phenanthrene - Naphthalene - Quinoline - Tetrahydroisoquinoline - Anisole - Aralkylamine - Alkyl aryl ether - Benzenoid - Tertiary aliphatic amine - Tertiary amine - Organoheterocyclic compound - Azacycle - Ether - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Amine - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as aporphines. These are quinoline alkaloids containing the dibenzo[de,g]quinoline ring system or a dehydrogenated derivative thereof.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
I2301677Certificate of AnalysisJun 10, 2025 N115702
E2323481Certificate of AnalysisFeb 07, 2025 N115702
L2212259Certificate of AnalysisNov 03, 2022 N115702
Propiedades químicas y físicas
Peso molecular295.400 g/mol
XLogP33.400
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass295.157 Da
Monoisotopic Mass295.157 Da
Topological Polar Surface Area21.700 Ų
Heavy Atom Count22
Formal Charge0
Complexity401.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Yuhuan Chen, Qiwen Chen, Xiaozhong Wang, Fan Sun, Yawei Fan, Xiaoru Liu, Hongyan Li, Zeyuan Deng.  (2019)  Hemostatic action of lotus leaf charcoal is probably due to transformation of flavonol aglycons from flavonol glycosides in traditional Chinses medicine.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:31678413] [10.1016/j.jep.2019.112364]
2. Li Zizhuo, Chen Yaodong, An Tingting, Liu Pengfei, Zhu Jiyuan, Yang Haichao, Zhang Wei, Dong Tianxiu, Jiang Jian, Zhang Yu, Jiang Maitao, Yang Xiuhua.  (2019)  RETRACTED ARTICLE: Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.  JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,  38  (1): (1-15).  [PMID:30922391] [10.1186/s13046-019-1134-y]
3. Lina Zhang, Jinghua Gao, Peng Tang, Li Chong, Yue Liu, Peng Liu, Xin Zhang, Li Chen, Chen Hou.  (2018)  Nuciferine inhibits LPS-induced inflammatory response in BV2 cells by activating PPAR-γ.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:30056259] [10.1016/j.intimp.2018.07.015]
4. Shixiang Chen, Bochen Wei, Lili Wen, Penglian Wei, Yunlin Fu.  (2024)  Metabolomics analysis of bioactive compositions of Michelia macclurei Dany and its antioxidant and enzyme inhibitory activities.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  105  (1): (635-648).  [PMID:39230063] [10.1002/jsfa.13860]
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