Ostarine (GTx-024) - Moligand™,≥99% , Androgen Receptor modulator, CAS No.841205-47-8, Androgen Receptor modulator

CAS: 841205-47-8 Cat. No.: O127397 Peso molecular: 389.33 Beilstein Registry Number: 10201846 Número EC: 106-553-5
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
(2R, 4R)-(-)-pentanediol | BCP28483 | AC-30221 | AMY38131 | s1174 | (2S)-3-(4-Cyanophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide | Enobosarm (USAN) | MK-2866 (GTx-024) | AKOS005266718 | Ostarine (MK2866) | MK-2866; GTX024;((
Storage
Almacenar a -20°C,cargado con argón
Shipped In
Hielera + almohadillas de hielo
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
10mg
O127397-10mg
6
59,90US$
50mg
O127397-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
199,90US$
250mg
O127397-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
819,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™,≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Almacenar a -20°C,cargado con argón Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

El MK-2866 (GTx-024) es un modulador selectivo del receptor androgénico (SARM) con Ki de 3,8 nM, y es selectivo para los tejidos de los órganos anabolizantes. Fase 3.
Modulador del receptor androgénico humano. La Ostarina a la concentración de 10 nM modula la actividad transcripcional del RA en células CV-1 cotransfectadas con un vector de expresión del RA humano, un vector reportero de luciferasa y un vector β-galactosidasa de control, con una actividad relativa del 94%-100% de la activación transcripcional observada para 1 nM de DHT.

Specifications

Sinónimos
(2R, 4R)-(-)-pentanediol | BCP28483 | AC-30221 | AMY38131 | s1174 | (2S)-3-(4-Cyanophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide | Enobosarm (USAN) | MK-2866 (GTx-024) | AKOS005266718 | Ostarine (MK2866) | MK-2866; GTX024;((
Especificaciones y pureza
Moligand™, ≥99%
Mecanismos bioquímicos y fisiológicos
Ostarine (MK-2866) es un modulador del receptor de andrógenos (SARM) con una ED50 de 0, 44 mg/día. Ostarine (MK-2866) tiene actividad anabólica. La ausencia de aumentos del PSA en los hombres y el crecimiento del pelo en las mujeres corroboraron aún más lo
Condiciones de almacenamiento de almacenamiento
Almacenar a -20°C, cargado con argón
Enviado en
Hielera + almohadillas de hielo
Grado
Moligand™
Tipo de acción
MODULATOR
Mecanismo de acción
Androgen Receptor modulator
Pureza
≥99%
Propiedades del producto
ALogP2.7
Nombres e identificadores
Sonrisas canónicasCC(COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
IUPAC Name(2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
InChIKeyJNGVJMBLXIUVRD-SFHVURJKSA-N
INCHI1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1
Isómeros SMILES C[C@](COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
Peso molecular 389.33
Beilstein 10201846
Reaxy-Rn 25761942
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25761942&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassTrifluoromethylbenzenes
Intermediate Tree Nodes Not available
Direct ParentTrifluoromethylbenzenes
Alternative Parents Anilides  Phenoxy compounds  Phenol ethers  N-arylamides  Benzonitriles  Alkyl aryl ethers  Tertiary alcohols  Secondary carboxylic acid amides  Nitriles  Organopnictogen compounds  Organofluorides  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  Alkyl fluorides  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Trifluoromethylbenzene - Anilide - Phenoxy compound - Benzonitrile - N-arylamide - Phenol ether - Alkyl aryl ether - Tertiary alcohol - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Ether - Carbonitrile - Nitrile - Alcohol - Organofluoride - Organohalogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Alkyl halide - Alkyl fluoride - Organic nitrogen compound - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as trifluoromethylbenzenes. These are organofluorine compounds that contain a benzene ring substituted with one or more trifluoromethyl groups.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
AR Tclin Androgen receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LNCaP (8286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CWR22R (2180 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VCaP (1078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeFechaArticulo
C2611621Certificate of AnalysisMar 20, 2026 O127397
C2611627Certificate of AnalysisMar 20, 2026 O127397
C2611620Certificate of AnalysisMar 20, 2026 O127397
C2611645Certificate of AnalysisMar 20, 2026 O127397
G1521068Certificate of AnalysisFeb 03, 2023 O127397
Propiedades químicas y físicas
SolubilidadDMSO
Peso molecular389.300 g/mol
XLogP32.700
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass389.099 Da
Monoisotopic Mass389.099 Da
Topological Polar Surface Area106.000 Ų
Heavy Atom Count28
Formal Charge0
Complexity658.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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