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OTS186935 hydrochloride - ≥99% , CAS No.O658722
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori
Appearance:Solid
IC50& Target:IC50: 6.49 nM (SUV39H2)
In Vitro:OTS186935 hydrochloride inhibits A549 cell growth with an IC 50 of 0.67 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo:OTS186935 hydrochloride (10mg/kg or 25mg/kg; intravenously; once daily for 14 days) exhibits growth suppressive effects in human cancer cell line derived xenograft models. MCE has not independently confirmed the accuracy of these methods. They are
Biological Activity:OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori
Specifications
Especificaciones y pureza
≥99%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Desiccated
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥99%
Nombres e identificadores
| Sonrisas canónicas | COC1=C(Cl)C=C(C2=CN3C=CC(N4C[C@@H](NCC5=CC=NC=C5)CC4)=CC3=N2)C(OC)=C1.[H]Cl.[8/5] |
|---|---|
| Peso molecular | 522.31 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | H2O : 50 mg/mL (95.73 mM; Need ultrasonic) DMSO : 25 mg/mL (47.86 mM; Need ultrasonic) |
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