Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
AR, ≥99% AR for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 45 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
p-Toluidine is an aromatic amine. It can be detected in the water samples by homogeneous liquid-liquid extraction followed by ion mobility spectrometry (HLLE-IMS).
| Pubchem Sid | 488180575 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488180575 |
| Sonrisas canónicas | CC1=CC=C(C=C1)N |
| IUPAC Name | 4-methylaniline |
| InChIKey | RZXMPPFPUUCRFN-UHFFFAOYSA-N |
| INCHI | 1S/C7H9N/c1-6-2-4-7(8)5-3-6/h2-5H,8H2,1H3 |
| Isómeros SMILES | CC1=CC=C(C=C1)N |
| WGK Alemania | 2 |
| RTECS | XU3150000 |
| PubChem CID | 7813 |
| Número ONU | 3451 |
| Grupo de embalaje | II |
| Peso molecular | 107.15 |
| Beilstein | 471281 |
| Reaxy-Rn | 471281 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Toluenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aminotoluenes |
| Alternative Parents | Aniline and substituted anilines Primary amines Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Aminotoluene - Aniline or substituted anilines - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as aminotoluenes. These are organic aromatic compounds containing a benzene that carries a single methyl group and one amino group. |
| External Descriptors | a cation |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Mar 28, 2025 | T108450 | |
| Certificate of Analysis | Mar 28, 2025 | T108450 | |
| Certificate of Analysis | Mar 28, 2025 | T108450 | |
| Certificate of Analysis | Mar 28, 2025 | T108450 | |
| Certificate of Analysis | Nov 20, 2023 | T108450 | |
| Certificate of Analysis | Jun 01, 2023 | T108450 | |
| Certificate of Analysis | Jun 01, 2023 | T108450 | |
| Certificate of Analysis | Jun 01, 2023 | T108450 | |
| Certificate of Analysis | Jun 01, 2023 | T108450 | |
| Certificate of Analysis | Jun 01, 2023 | T108450 | |
| Certificate of Analysis | Jun 01, 2023 | T108450 | |
| Certificate of Analysis | Aug 25, 2021 | T108450 | |
| Certificate of Analysis | Aug 25, 2021 | T108450 |
| Solubilidad | Soluble in ethanol, pyridine, diethyl ether, acetone, carbon tetrachloride, methanol, carbon disulfide, oils and dilute acids. |
|---|---|
| Sensibilidad | Heat,Light & Air Sensitive |
| Índice de refracción | 1.5532 |
| Punto de inflamación (°F) | 188.6 °F |
| Punto de inflamación (°C) | 87 °C |
| Punto de ebullición (°C) | 200~201°C |
| Punto de fusión (°C) | 41-46°C |
| Peso molecular | 107.150 g/mol |
| XLogP3 | 1.400 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 107.073 Da |
| Monoisotopic Mass | 107.073 Da |
| Topological Polar Surface Area | 26.000 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 62.800 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Hongxing Yuan, Wei Gao, Xinhao Wan, Jianqi Ye, Dan Wen. (2023) Tuning the surface electronic structure of noble metal aerogels to promote the electrocatalytic oxygen reduction. Journal of Energy Chemistry, [PMID:] [10.1016/j.jechem.2023.11.006] |
| 2. Jiajie Lyu, Beibei Ji, Nan Wu, Wei Liao, Changping Yin, Shuxin Bai, Suli Xing. (2023) The effect of substituent group in allyl benzoxazine on the thermal, mechanical and dielectric properties of modified bismaleimide. REACTIVE & FUNCTIONAL POLYMERS, [PMID:] [10.1016/j.reactfunctpolym.2023.105673] |
| 3. Xiaoya Fu, Xia Wang, Zhining Xia, Yike Huang. (2022) Preparation of dummy molecularly imprinted polymers for selective extraction of aromatic amine genotoxic impurities. JOURNAL OF CHROMATOGRAPHY A, [PMID:36379197] [10.1016/j.chroma.2022.463617] |
| 4. Shuangying Li, Qingxiang Zhou, Zhi Li, Menghua Liu, Yanhui Li, Chunmao Chen. (2022) Effective and selective measurement of 2,4-dinitroaniline utilizing constructed fluorescent carbon dots sensor derived from vitamin B1. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:36323094] [10.1016/j.saa.2022.122040] |
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| 6. Xiwei Xu, Songqi Ma, Hongzhi Feng, Jianfan Qiu, Sheng Wang, Zhen Yu, Jin Zhu. (2021) Dissociate transfer exchange of tandem dynamic bonds endows covalent adaptable networks with fast reprocessability and high performance. Polymer Chemistry, 12 (36): (5217-5228). [PMID:] [10.1039/D1PY01045J] |
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| 8. Shichao Xu, Xiaojing Zeng, Songlin Dai, Jing Wang, Yuxiang Chen, Jie Song, Yunfei Shi, Xian Cheng, Shengliang Liao, Zhendong Zhao. (2020) Turpentine Derived Secondary Amines for Sustainable Crop Protection: Synthesis, Activity Evaluation and QSAR Study. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:32975941] [10.1021/acs.jafc.0c01909] |
| 9. Zong-Da Du, Yuan-Yuan Cui, Cheng-Xiong Yang. (2020) Fabrication of spherical silica amino-functionalized microporous organic network composites for high performance liquid chromatography. TALANTA, [PMID:33076117] [10.1016/j.talanta.2020.121570] |
| 10. Zhipeng Xie, Mingfeng Yang, Le Luo, Yiping Lv, Kangjin Song, Simin Liu, Daqi Chen, Jiahai Wang. (2020) Nanochannel sensor for sensitive and selective adamantanamine detection based on host-guest competition. TALANTA, [PMID:32887115] [10.1016/j.talanta.2020.121213] |
| 11. Wenhao Wu, Yuan Lan, Yaxiong Zeng, Daohui Lin, Kun Yang. (2020) Nonlinear sorption of phenols and anilines by organobentonites: Nonlinear partition and space limitation for partitioning. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:32492612] [10.1016/j.scitotenv.2020.139609] |
| 12. Chao Zhu, Zarak Mahmood, Abdul Saboor Arshad, Jia Liu, Hongrui Ma. (2020) Recovery of o-toluidine and p-toluidine from wastewater by silicon rubber membrane extraction. Environmental Technology & Innovation, [PMID:] [10.1016/j.eti.2020.100873] |
| 13. Li-Hua Du, Rui-Jie Long, Miao Xue, Ping-Feng Chen, Meng-Jie Yang, Xi-Ping Luo. (2020) Continuous-Flow Synthesis of β-Amino Acid Esters by Lipase-Catalyzed Michael Addition of Aromatic Amines. Catalysts, 10 (4): (432). [PMID:] [10.3390/catal10040432] |
| 14. Chen Fen, Wu Ligui, Xiao Xiaoyu, Rong Lingling, Li Mi, Zou Xiaoming. (2020) Mixture toxicity of zinc oxide nanoparticle and chemicals with different mode of action upon Vibrio fischeri. Environmental Sciences Europe, 32 (1): (1-10). [PMID:] [10.1186/s12302-020-00320-x] |
| 15. Wenhao Wu, Gangfen Miao, Xinxin Yan, Baoshan Xing, Kun Yang. (2019) Correlations and prediction of adsorption capacity and affinity of aromatic compounds on activated carbons. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:31837858] [10.1016/j.scitotenv.2019.135457] |
| 16. Ren Liufen, Lin Daohui, Yang Kun. (2019) Correlations and nonlinear partition of nonionic organic compounds by humus-like substances humificated from rice straw. Scientific Reports, 9 (1): (1-10). [PMID:31641156] [10.1038/s41598-019-51406-3] |
| 17. Dan Yao, Tonghui Wei, Lichao Shang, Hui Na, Chengji Zhao. (2019) A comparative study of side-chain-type poly(ether ether ketone) anion exchange membrane functionalized with different hetero-cycloaliphatic quaternary ammonium groups. RSC Advances, 9 (14): (7975-7983). [PMID:35521211] [10.1039/C8RA09840A] |
| 18. Yujuan Cao, Song Wang, Wei Wu, Hong Peng, Ying Yu, Debin Zhu. (2019) Cucurbit[6]uril modified CdTe quantum dots fluorescent probe and its selective analysis of p-nitroaniline in environmental samples. TALANTA, [PMID:30952313] [10.1016/j.talanta.2019.02.084] |
| 19. Rong Wang, Zhenkun Mao, Zilin Chen. (2018) Monolithic column with polymeric deep eutectic solvent as stationary phase for capillary electrochromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:30274692] [10.1016/j.chroma.2018.09.046] |
| 20. Zaiming Chen, Wenjie Ji. (2018) Sorption of ionizable organic chemicals to carbonaceous adsorbents: Solution pH change and contributions of different species. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:30180315] [10.1016/j.scitotenv.2018.08.033] |
| 21. Lu-Liang Wang, Cheng-Xiong Yang, Xiu-Ping Yan. (2017) In Situ Growth of Covalent Organic Framework Shells on Silica Microspheres for Application in Liquid Chromatography. ChemPlusChem, 82 (6): (933-938). [PMID:31961565] [10.1002/cplu.201700223] |
| 22. Dandan Wu, Yanqiao Zhang, Ming Wen, Hao Fang, Qingsheng Wu. (2017) Fe3O4/FeNi Embedded Nanostructure and Its Kinetic Law for Selective Catalytic Reduction of p-Nitrophenyl Compounds. INORGANIC CHEMISTRY, [PMID:28426207] [10.1021/acs.inorgchem.7b00304] |
| 23. Lu Yin, Yin Zhao, Meng Liu, Nianchen Zhou, Wei Zhang, Xiulin Zhu. (2017) Induction of supramolecular chirality by chiral solvation in achiral Azo polymers with different spacer lengths and push–pull electronic substituents: where will chiral induction appear?. Polymer Chemistry, 8 (12): (1906-1913). [PMID:] [10.1039/C7PY00130D] |
| 24. Haoran Yuan, Xiang Fang, Qiyi Ma, Jianyong Mao, Kexian Chen, Zhirong Chen, Haoran Li. (2016) New mechanistic insight into the aerobic oxidation of methylaromatic compounds catalyzed by Co–Mn–Br and its applications. JOURNAL OF CATALYSIS, [PMID:] [10.1016/j.jcat.2016.04.014] |
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| 43. Xue Zhang, Xu Tong, Zhiqi Zhou, Changhai Zhang, Tiandong Zhang, Wenju Wu, Chao Wang, Shuya Fu, Chao Yin, Qingguo Chi. (2026) Manipulating Polymer Side-Chain Configuration via Substituent Steric Hindrance for Enhanced High-Temperature Capacitive Energy Storage Performance. ADVANCED FUNCTIONAL MATERIALS, [PMID:] [10.1002/adfm.202530435] |
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| 45. Linzhu Xu, Qingyun Zhao, Birong Zeng, Jie Song, Ziyun Chen, Yilin Su, Zhenlong Luo, Yiting Xu, Conghui Yuan, Lizong Dai. (2026) Azobenzene-Based Light-Sensitive Polyurethane Elastomers with Enhanced Self-Healing and Soft–Hard Switching Proerties. ACS Applied Polymer Materials, [PMID:] [10.1021/acsapm.6c00546] |
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