PARP7-IN-14 - ≥98% , CAS No.P659390

CAS: P659390 Cat. No.: P659390 Peso molecular: 534.46

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.

Appearance:Solid

In Vitro:PARP7-IN-14 (I-1) inhibits CT26 cell lines with the IC 50 value of 12.85 μM and shows some anti-proliferative effect on tumors. PARP7-IN-14 (I-1) (0-4 μM) promotes mRNA expression levels of IFN-β and CXCL10 and induces a concentration-dependent incre

In Vivo:PARP7-IN-14 (I-1) (p.o., 25-100mg/kg, twice daily, 14 days) significantly inhibits tumour growth in CT26 tumour-bearing mice, with a 67% reduction in mean tumour volume in mice treated with I-1 compared to controls, and does not cause weight loss or othe

Biological Activity:PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.

Specifications

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: O=C1NN=CC(N[C@H](CN2CC(C(N3CCN(CC3)C4=NC=C(C=N4)C(F)(F)F)=O)C2)C)=C1C(F)(F)F
• Peso molecular: 534.46