PC Alkyne-PEG4-NHS ester - ≥95% , CAS No.1802907-98-7

CAS: 1802907-98-7 Cat. No.: P596694 Peso molecular: 653.63

GRADE & PURITY ≥95%

Synonyms

PC Alkyne-PEG4-NHS ester | 2,5-Dioxopyrrolidin-1-yl (1-(5-methoxy-2-nitro-4-((17-oxo-4,7,10,13-tetraoxa-16-azaicos-1-yn-20-yl)oxy)phenyl)ethyl) carbonate

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Specifications

Sinónimos

PC Alkyne-PEG4-NHS ester | 2, 5-Dioxopyrrolidin-1-yl (1-(5-methoxy-2-nitro-4-((17-oxo-4, 7, 10, 13-tetraoxa-16-azaicos-1-yn-20-yl)oxy)phenyl)ethyl) carbonate

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

• Sonrisas canónicas: CC(C1=CC(=C(C=C1[N+](=O)[O-])OCCCC(=O)NCCOCCOCCOCCOCC#C)OC)OC(=O)ON2C(=O)CCC2=O
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 1-[5-methoxy-2-nitro-4-[4-oxo-4-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethylamino]butoxy]phenyl]ethyl carbonate
• InChIKey: AOWMPLACVFKCJJ-UHFFFAOYSA-N
• INCHI: 1S/C29H39N3O14/c1-4-10-40-13-15-42-17-18-43-16-14-41-12-9-30-26(33)6-5-11-44-25-20-23(32(37)38)22(19-24(25)39-3)21(2)45-29(36)46-31-27(34)7-8-28(31)35/h1,19-21H,5-18H2,2-3H3,(H,30,33)
• Isómeros SMILES: CC(C1=CC(=C(C=C1[N+](=O)[O-])OCCCC(=O)NCCOCCOCCOCCOCC#C)OC)OC(=O)ON2C(=O)CCC2=O
• Peso molecular: 653.63

Propiedades químicas y físicas

• Peso molecular: 653.600 g/mol
• XLogP3: 0.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 24
• Exact Mass: 653.243 Da
• Monoisotopic Mass: 653.243 Da
• Topological Polar Surface Area: 203.000 Ų
• Heavy Atom Count: 46
• Formal Charge: 0
• Complexity: 1010.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1