PF-3450074 - Moligand™, 10 mM in DMSO , CAS No.1352879-65-2

CAS: 1352879-65-2 Cat. No.: P1495250 Peso molecular: 425.52 PubChem CID: 49800090

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

PF-3450074 (PF-74) is a specifical inhibitor of? HIV-1 capsid protein ( CA ) and displays a broad-spectrum inhibition of HIV isolates with submicromolar potency ( EC 50 =8-640 nM). PF-3450074 (PF-74) acts at an early stage of HIV-1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle . CPSF6: nuclear host factors cleavage and polyadenylation specific factor 6; NUP153: nucleoporin 153.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Nombres e identificadores

• Isómeros SMILES: CC1=C(C2=CC=CC=C2N1)CC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N(C)C4=CC=CC=C4
• WGK Alemania: 3
• PubChem CID: 49800090
• Peso molecular: 425.52