[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2, CAS No.213130-17-7

CAS: 213130-17-7 Cat. No.: P287978 Peso molecular: 1367.6

Specifications

Product Name

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2, CAS No.213130-17-7

Mecanismos bioquímicos y fisiológicos

Potente agonista del receptor de nociceptina (ORL1), demostrado tanto in vitro como in vivo. También se ha descrito un antagonismo selectivo y competitivo del receptor de nociceptina (pA2= 7, 02 y 6, 75 en el íleon de cobaya y en los conductos deferentes de

Secuencia

FGGFTGARKSARK(Modifications: Phe-1 - Gly-2 peptide bond replace with Psi-(CH2-NH), Lys-13 = C-terminal amide)

CAS

213130-17-7

Tipo de molécula

Protein

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C,Desecado

Enviado en

Hielera + almohadillas de hielo

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic Polymers
    • Clase Polypeptides

• Kingdom: Organic compounds
• Superclass: Organic Polymers
• Clase: Polypeptides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Polypeptides
• Alternative Parents: Peptides Phenylalanine and derivatives N-acyl-alpha amino acids and derivatives Serine and derivatives Alpha amino acid amides Alanine and derivatives Amphetamines and derivatives Aralkylamines N-acyl amines Secondary carboxylic acid amides Secondary alcohols Primary carboxylic acid amides Guanidines Propargyl-type 1,3-dipolar organic compounds Carboximidamides Dialkylamines Carbonyl compounds Monoalkylamines Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Polypeptide - Alpha peptide - Phenylalanine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Serine or derivatives - Alanine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - Aralkylamine - Fatty acyl - Monocyclic benzene moiety - Fatty amide - Benzenoid - N-acyl-amine - Amino acid or derivatives - Carboxamide group - Guanidine - Secondary carboxylic acid amide - Primary carboxylic acid amide - Secondary alcohol - Secondary amine - Organic 1,3-dipolar compound - Carboxylic acid derivative - Secondary aliphatic amine - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Primary alcohol - Primary amine - Organic nitrogen compound - Carbonyl group - Amine - Hydrocarbon derivative - Alcohol - Organic oxygen compound - Primary aliphatic amine - Organooxygen compound - Organic oxide - Organonitrogen compound - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

OPRL1 Tchem Nociceptin receptor (3823 Activities)

Discover Target: OPRL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción