Phloretic acid - ≥98% , CAS No.501-97-3

CAS: 501-97-3 Cat. No.: P106355 Peso molecular: 166.17 Beilstein Registry Number: 2209841 Número EC: 207-931-3
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
3-(4-HYDROXYPHENYL) PROPIONIC ACID | AT13193 | CCG-266325 | SCHEMBL35486 | 4-Hydroxybenzenepropanoate | 4-hydroxy-benzenepropanoate | NSC65596 | NSC-65596 | Dihydro-p-coumarate | 3-(4'-Hydroxyphenyl)-propionate | 3-(4-Hydroxy-phenyl)-propionate | 3-(4-Hyd
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5g
P106355-5g
4
9,90US$
25g
P106355-25g
1
10,90US$
100g
P106355-100g
7

24,90US$

37,90US$
Guardar 13,00 US$ (34.30%)
500g
P106355-500g
1

81,90US$

122,90US$
Guardar 41,00 US$ (33.36%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
3-(4-HYDROXYPHENYL) PROPIONIC ACID | AT13193 | CCG-266325 | SCHEMBL35486 | 4-Hydroxybenzenepropanoate | 4-hydroxy-benzenepropanoate | NSC65596 | NSC-65596 | Dihydro-p-coumarate | 3-(4'-Hydroxyphenyl)-propionate | 3-(4-Hydroxy-phenyl)-propionate | 3-(4-Hyd
Especificaciones y pureza
≥98%
Condiciones de almacenamiento de almacenamiento
Room temperature
Enviado en
Normal
Pureza
≥98%
Nombres e identificadores
Pubchem Sid488181127
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181127
Sonrisas canónicasC1=CC(=CC=C1CCC(=O)O)O
IUPAC Name3-(4-hydroxyphenyl)propanoic acid
InChIKeyNMHMNPHRMNGLLB-UHFFFAOYSA-N
INCHI1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12)
Isómeros SMILES C1=CC(=CC=C1CCC(=O)O)O
WGK Alemania 3
RTECS MW5342000
Peso molecular 166.17
Beilstein 2209841
Reaxy-Rn 2209841
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2209841&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClasePhenylpropanoic acids
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPhenylpropanoic acids
Alternative Parents 1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents 3-phenylpropanoic-acid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Benzenoid - Monocyclic benzene moiety - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as phenylpropanoic acids. These are compounds with a structure containing a benzene ring conjugated to a propanoic acid.
External Descriptors hydroxy monocarboxylic acid
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
DNMT1 Tclin DNA (cytosine-5)-methyltransferase 1 (978 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIK3R1 Tchem PI3-kinase p110-alpha/p85-alpha (2589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
PIK3CA PI3-kinase p110-alpha subunit (51 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plutella xylostella (1838 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Spodoptera exigua (540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phenol oxidase (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

26 results found

Lot NumberCertificate TypeFechaArticulo
C2223472Certificate of AnalysisJan 19, 2026 P106355
K2127569Certificate of AnalysisSep 08, 2025 P106355
K2127568Certificate of AnalysisSep 08, 2025 P106355
K2506674Certificate of AnalysisJul 23, 2024 P106355
K2506673Certificate of AnalysisJul 23, 2024 P106355
K2505687Certificate of AnalysisJul 19, 2024 P106355
K2505711Certificate of AnalysisJun 26, 2024 P106355
F2404375Certificate of AnalysisApr 16, 2024 P106355
F2404376Certificate of AnalysisApr 16, 2024 P106355
A2607099Certificate of AnalysisApr 16, 2024 P106355
F2404374Certificate of AnalysisApr 16, 2024 P106355
D2627017Certificate of AnalysisApr 16, 2024 P106355
D2001062Certificate of AnalysisJan 19, 2024 P106355
G23051278Certificate of AnalysisJun 12, 2023 P106355
G23051280Certificate of AnalysisJun 12, 2023 P106355
G23051281Certificate of AnalysisJun 12, 2023 P106355
G23051282Certificate of AnalysisJun 12, 2023 P106355
G1513061Certificate of AnalysisApr 11, 2023 P106355
D2324719Certificate of AnalysisDec 13, 2022 P106355
B2302939Certificate of AnalysisDec 13, 2022 P106355
B2302938Certificate of AnalysisDec 13, 2022 P106355
B2302936Certificate of AnalysisDec 13, 2022 P106355
B23021231Certificate of AnalysisDec 13, 2022 P106355
B23021223Certificate of AnalysisDec 13, 2022 P106355
B23021046Certificate of AnalysisDec 13, 2022 P106355
C2223422Certificate of AnalysisMar 04, 2022 P106355

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Propiedades químicas y físicas
SolubilidadSoluble in water.
Punto de fusión (°C)130°C
Peso molecular166.170 g/mol
XLogP31.200
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass166.063 Da
Monoisotopic Mass166.063 Da
Topological Polar Surface Area57.500 Ų
Heavy Atom Count12
Formal Charge0
Complexity148.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Jingkai Liu, Liyue Zhang, Xinbei Zhu, Qing Chen, Kan Zhang, Xiaoqing Liu.  (2023)  Design of a Low-Temperature Ring-Opening Benzoxazine System Using a Supramolecular Hydrogen-Bond Structure.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.3c01107]
2. Lili Hao, Shijia Zhao, Shiqi Hao, Yuxin He, Miao Feng, Ke Zhou, Yiyan He, Jiquan Yang, Hongli Mao, Zhongwei Gu.  (2023)  Functionalized gelatin-alginate based bioink with enhanced manufacturability and biomimicry for accelerating wound healing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37044319] [10.1016/j.ijbiomac.2023.124364]
3. Weicheng Cai, Zhaolin Li, Hui Huang, Xuejing Li, Jian Zhao, Pengbo Liu, Yajun Wu, Mingchang Liu, Jian Wang.  (2023)  A Compact UV-LED-Induced Fluorescence With Short Metal Capillary and Low Light Leakage: Application to Noninvasive Glucose Detection.  IEEE SENSORS JOURNAL,  23  (8): (8366-8374).  [PMID:] [10.1109/JSEN.2023.3257834]
4. Peng Ding, Qianqian Wei, Ning Tian, Xiaoyue Ding, Ling Wang, Bin Wang, Oseweuba Valentine Okoro, Amin Shavandi, Lei Nie.  (2022)  Enzymatically crosslinked hydrogel based on tyramine modified gelatin and sialylated chitosan.  Biomedical Materials,  18  (1): (015006).  [PMID:36322975] [10.1088/1748-605X/ac9f90]
5. Hui-Ying Wang, Cheng Qu, Meng-Ning Li, Chao-Ran Li, Run-Zhou Liu, Zifan Guo, Ping Li, Wen Gao, Hua Yang.  (2022)  Time-Series-Dependent Global Data Filtering Strategy for Mining and Profiling of Xenobiotic Metabolites in a Dynamic Complex Matrix: Application to Biotransformation of Flavonoids in the Extract of Ginkgo biloba by Gut Microbiota.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:36331925] [10.1021/acs.jafc.2c03080]
6. Ru Xu, Dongdong Zhang, Ji Tan, Naijian Ge, Dan Liu, Junyu Liu, Liping Ouyang, Hongqin Zhu, Yuqin Qiao, Jiajun Qiu, Shijie Zhu, Xuanyong Liu.  (2022)  A multifunctional cascade bioreactor based on a layered double oxides composite hydrogel for synergetic tumor chemodynamic/starvation/photothermal therapy.  Acta Biomaterialia,      [PMID:36115653] [10.1016/j.actbio.2022.09.024]
7. Peng Wei, Longlong Li, Li Wang, Jinfei Yan, Nan Zeng, Longxin Li, Nan Sun, Lu Bai, Helong Li, Yifeng Zhang.  (2022)  Synthesis and properties of high performance biobased liquid crystal copolyesters toward load-bearing bone repair application.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2022.111278]
8. Yao Liu, Ruifang Sun, XiaoPing Lin, Lanlan Wu, Hengying Chen, Siwen Shen, Yan Li, Yuanhuan Wei, Guifang Deng.  (2022)  Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:35567986] [10.1016/j.biopha.2022.113078]
9. Qian Tao, Julong Zhong, Rui Wang, Yuzhu Huang.  (2021)  Ionic and Enzymatic Multiple-Crosslinked Nanogels for Drug Delivery.  Polymers,  13  (20): (3565).  [PMID:34685323] [10.3390/polym13203565]
10. Feng Li, Liping Wang, Yilei Cai, Yihuo Luo, Xianai Shi.  (2021)  Safety assessment of desaminotyrosine: Acute, subchronic oral toxicity, and its effects on intestinal microbiota in rats.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:33636197] [10.1016/j.taap.2021.115464]
11. Yongheng Yin, Huimin Liu, Hongbo Li, Sheng Li, Hanfang Liu, Chongbin Wang, Chengyun Gao.  (2020)  Efficient sol-gel synthesis of zwitterion functionalized titania for nanofiltration membrane with enhanced selectivity and antifouling performance.  Journal of the Taiwan Institute of Chemical Engineers,      [PMID:] [10.1016/j.jtice.2020.05.003]
12. Yang Li, Ying Peng, Ping Ma, Mengyue Wang, Chongsheng Peng, Pengfei Tu, Xiaobo Li.  (2019)  In vitro and in vivo metabolism of Cistanche tubulosa extract in normal and chronic unpredictable stress-induced depressive rats.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:31352203] [10.1016/j.jchromb.2019.121728]
13. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang.  (2018)  Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols.  Food & Function,  (9): (4858-4864).  [PMID:30156246] [10.1039/C8FO00609A]
14. Shiling Liu, Siying Qin, Tengfei Zhang, Heng Zhang, Junqi Zhu, Xiaoli Li, Yuanfu Li, Feng Zhao.  (2025)  Basing target enzyme study the enantioselective bioactivity action mechanism of flusulfinam, a novel HPPD inhibitor herbicide.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:40082037] [10.1016/j.pestbp.2025.106346]
15. Jinyuan Zhao, Hongwang Yang, Zhanxin Jiang, Jingquan Wang, Chuncai Kong, Zhimao Yang, Tong Wang, Hao Zhu.  (2024)  Fabrication of acid-activated dispersive palygorskite nanorods supported copper manganese composite oxide for catalytic oxidation of toluene.  Materials Today Communications,      [PMID:] [10.1016/j.mtcomm.2024.108269]
16. Xinjun He, Mengqiao Gao, Fukun Li, Zhiyang Tang, Jie Qu, Jinxing Long, Qiang Zeng, Xuehui Li.  (2025)  Catalytic hydrogenolysis of lignin under syngas: the enhancement on the Cβ-O bond cleavage with CO.  GREEN CHEMISTRY,      [PMID:] [10.1039/D5GC01618E]
17. Julio Abel Alfredo dos Santos Simone Come, Yibin Zhuang, Tianzhen Li, Simone Brogi, Sandra Gemma, Tao Liu, Edson Roberto da Silva.  (2022)  In Vitro and In Silico Analyses of New Cinnamid and Rosmarinic Acid-Derived Compounds Biosynthesized in Escherichia coli as Leishmania amazonensis Arginase Inhibitors.  Pathogens,  11  (9): (1020).  [PMID:36145452] [10.3390/pathogens11091020]
18. Hong Liang, Xiaobing Chen, Rongrong Jin, Bowen Ke, Matthias Barz, Hua Ai, Yu Nie.  (2020)  Integration of Indocyanine Green Analogs as Near-Infrared Fluorescent Carrier for Precise Imaging-Guided Gene Delivery.  Small,  16  (10): (1906538).  [PMID:32022444] [10.1002/smll.201906538]
19. Yang Li, Ying Peng, Mengyue Wang, Pengfei Tu, Xiaobo Li.  (2017)  Human Gastrointestinal Metabolism of the Cistanches Herba Water Extract in Vitro: Elucidation of the Metabolic Profile Based on Comprehensive Metabolite Identification in Gastric Juice, Intestinal Juice, Human Intestinal Bacteria, and Intestinal Microsomes.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:28771352] [10.1021/acs.jafc.7b02829]
20. Yuheng Chen, Junhui Li, Jichao Zhang, Yuchen Liu, Caihong Chen, Yumin Xia, Yanping Wang, Peng Wei.  (2025)  Synthesis and properties of biobased aromatic liquid crystal copolyester with excellent thermal stability and fibre formation ability.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2025.2571749]
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