PI4KIIIbeta-IN-10 - 10mM in DMSO , CAS No.1881233-39-1

CAS: 1881233-39-1 Cat. No.: P656600 Peso molecular: 475.6 PubChem CID: 71549093

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC 50 of 3.6 nM.

In Vitro

PI4KIIIbeta-IN-10 (Compound 10) is a potent PI4KIIIβ inhibitor with very minor off-target inhibition of PI4KIIIβ related lipid kinases. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC 50 ~1 µM), PI3Kα (~10 µM), and PI4KIIIα (~3 µM), and <20% inhibition at concentrations up to 20 µM for PI4K2α, PI4K2β, and PI3Kβ. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:PI4KIIIβ 3.6 nM (IC 50 ) PI4KIIIα 3 μM (IC 50 ) PI3Kδ 720 nM (IC 50 ) PI3KC2γ 1 μM (IC 50 ) PI3Kα 10 μM (IC 50 ) PI3Kγ 20 μM (IC 50 )

Specifications

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC 50 of 3.6 nM.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Nombres e identificadores

• Isómeros SMILES: CC1=C(SC(=N1)NC(=O)C(C)(C)C)C2=CC(=C(C=C2)OC)S(=O)(=O)NC3=CC=C(C=C3)O
• CAS alternativo: 1881233-39-1
• PubChem CID: 71549093
• Peso molecular: 475.6