Pitavastatin - Moligand™, 10 mM in DMSO , CAS No.147511-69-1

CAS: 147511-69-1 Cat. No.: P1499322 Peso molecular: 421.46 Número EC: 643-092-3 PubChem CID: 5282452

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Isómeros SMILES: C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@H](C[C@H](CC(=O)O)O)O)C4=CC=C(C=C4)F
• PubChem CID: 5282452
• Peso molecular: 421.46

Propiedades químicas y físicas

• Punto de inflamación (°C): 372.3±31.5 ℃
• Punto de ebullición (°C): 692.0±55.0℃ at 760 mmHg

Referencias

1. Anning Yang, Hongwen Zhang, Huiping Zhang, Nan Li, Cong Chen, Xiaoling Yang, Jue Tian, Jianmin Sun, Guizhong Li, Yue Sun, Bin Liu, Yideng Jiang.  (2025)  Pitavastatin and resveratrol bio-nanocomplexes against hyperhomocysteinemia-induced atherosclerosis via blocking ferroptosis-related lipid deposition.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40043912] [10.1016/j.jconrel.2025.113598]

2. Yizhou Wu, Hongyan Zhou, Hao Liu, Jiayao Hu, Yue Sun, Wei Yan, Chunyi Tong, Ying Kong, Bin Liu.  (2025)  Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.  Acta Pharmaceutica Sinica B,      [PMID:40654339] [10.1016/j.apsb.2024.08.006]