Polydatin - Moligand™,10mM in DMSO , CAS No.65914-17-2

CAS: 65914-17-2 Cat. No.: P408531 Fórmula: C₂₀H₂₂O₈ Peso molecular: 390.38 Número EC: 683-198-7

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Piceid | β-D-Glucopyranoside, 3-hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Polydatin Polydatin (Piceid) is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.
In vitro

Polydatin, known as a PLA2 inhibitor, reduces Phospholipase A2 (PLA2) activity and sPLA2-IIA mRNA expression and mitigates LPS-induced lung injury by increasing increased Clara cell secretory protein (CCSP) expression.

In vivo

Pretreatment with Polydatin (15, 45, and 100 mg/kg) dose-dependently reduces sepsis-induced mortality and lung injury in cecal ligation and puncture (CLP-)induced sepsis mice through inhibiting CLP-induced serum tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) production, lung cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase isoform (iNOS) protein expressions and NF-kappaB activation. LD50: Mice 1g/kg (i.p.)
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Sinónimos

Piceid | β-D-Glucopyranoside, 3-hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl

Especificaciones y pureza

Moligand™,10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Polydatin (Piceid) is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

Isómeros SMILES

C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O

CAS alternativo

27208-80-6

Peso molecular

390.38

Reaxy-Rn

1604738

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1604738&ln=

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro
• Punto de fusión (°C): 223-226°C