Ponceau S - Suitable for molecular biology , CAS No.6226-79-5

CAS: 6226-79-5 Cat. No.: P109022 Peso molecular: 760.57 Número EC: 228-319-2
Disponible para pedir
GRADE & PURITY Suitable for molecular biology ? Molecular-biology grade — free of nucleases and contaminants that degrade DNA/RNA. Use in cloning, PCR, and nucleic-acid work needing clean reagents.
Synonyms
HB0819 | UNII-T1C2UGS05F | 3-Hydroxy-4-((2-sulfo-4-((4-sulfophenyl)diazenyl)phenyl)diazenyl)naphthalene-2,7-disulfonic acid, tetrasodium salt | AKOS015902723 | CHEBI:90319 | 2,7-Naphthalenedisulfonic acid,3-hydroxy-4-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
10g
P109022-10g
9
26,90US$
50g
P109022-50g
5
106,90US$
100g
P109022-100g
4
182,90US$
250g
P109022-250g
2
328,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Suitable for molecular biology Suitable for molecular biology for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Ponceau S is the sodium salt of a diazo dye. It is used to make a stain for rapid reversible staining of protein bands on nitrocellulose or PVDF membranes (Western blots) and also for staining protein on cellulose acetate membranes. The stain is reversed with water washes and aids in subsequent immunological detection. The following are two common stain formulations: 0.1% Ponceau S (w/v) in 5% acetic acid 2% Ponceau S (w/v) in 30% TCA, 30% sulfosalicylic acid

Specifications

Sinónimos
HB0819 | UNII-T1C2UGS05F | 3-Hydroxy-4-((2-sulfo-4-((4-sulfophenyl)diazenyl)phenyl)diazenyl)naphthalene-2, 7-disulfonic acid, tetrasodium salt | AKOS015902723 | CHEBI:90319 | 2, 7-Naphthalenedisulfonic acid, 3-hydroxy-4-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl
Especificaciones y pureza
Suitable for molecular biology
Condiciones de almacenamiento de almacenamiento
Room temperature
Enviado en
Normal
Grado
Suitable for molecular biology
Nombres e identificadores
Pubchem Sid488192212
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488192212
Sonrisas canónicasC1=CC(=CC=C1N=NC2=CC(=C(C=C2)N=NC3=C4C=CC(=CC4=CC(=C3O)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]
IUPAC Nametetrasodium;3-hydroxy-4-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]diazenyl]naphthalene-2,7-disulfonate
InChIKeyKQHKSGRIBYJYFX-UHFFFAOYSA-J
INCHI1S/C22H16N4O13S4.4Na/c27-22-20(43(37,38)39)10-12-9-16(41(31,32)33)6-7-17(12)21(22)26-25-18-8-3-14(11-19(18)42(34,35)36)24-23-13-1-4-15(5-2-13)40(28,29)30;;;;/h1-11,27H,(H,28,29,30)(H,31,32,33)(H,34,35,36)(H,37,38,39);;;;/q;4*+1/p-4
Isómeros SMILES C1=CC(=CC=C1N=NC2=CC(=C(C=C2)N=NC3=C4C=CC(=CC4=CC(=C3O)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]
WGK Alemania 3
RTECS QJ6600000
Peso molecular 760.57
Reaxy-Rn 6265648
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6265648&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseNaphthalenes
SubclassNaphthalene sulfonic acids and derivatives
Intermediate Tree Nodes Naphthalene sulfonates
Direct Parent2-naphthalene sulfonates
Alternative Parents Azobenzenes  2-naphthalene sulfonic acids and derivatives  Benzenesulfonic acids and derivatives  Benzenesulfonyl compounds  1-sulfo,2-unsubstituted aromatic compounds  Phenoxides  Sulfonyls  Organosulfonic acids  Azo compounds  Propargyl-type 1,3-dipolar organic compounds  Organopnictogen compounds  Organooxygen compounds  Organic sodium salts  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Azobenzene - 2-naphthalene sulfonic acid or derivatives - 2-naphthalene sulfonate - Benzenesulfonate - Arylsulfonic acid or derivatives - 1-sulfo,2-unsubstituted aromatic compound - Benzenesulfonyl group - Phenoxide - Monocyclic benzene moiety - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Azo compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic alkali metal salt - Organic sodium salt - Organic oxygen compound - Organopnictogen compound - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic salt - Organic nitrogen compound - Aromatic homopolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as 2-naphthalene sulfonates. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group at the 2-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot NumberCertificate TypeFechaArticulo
L2202200Certificate of AnalysisMay 20, 2026 P109022
L2202201Certificate of AnalysisMay 20, 2026 P109022
L2202396Certificate of AnalysisMay 20, 2026 P109022
G2523298Certificate of AnalysisMar 24, 2025 P109022
G2523416Certificate of AnalysisMar 24, 2025 P109022
H2504741Certificate of AnalysisMar 24, 2025 P109022
H2504742Certificate of AnalysisMar 24, 2025 P109022
B2511016Certificate of AnalysisFeb 17, 2025 P109022
D2324735Certificate of AnalysisJan 08, 2025 P109022
K2422242Certificate of AnalysisNov 26, 2024 P109022
J2418308Certificate of AnalysisOct 19, 2024 P109022
L2202282Certificate of AnalysisAug 15, 2024 P109022
F2417067Certificate of AnalysisNov 17, 2022 P109022
H2218089Certificate of AnalysisAug 30, 2022 P109022

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Propiedades químicas y físicas
SolubilidadSoluble in water (1 mg/ml). Insoluble in ether.
Peso molecular760.600 g/mol
XLogP3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count17
Rotatable Bond Count4
Exact Mass759.887 Da
Monoisotopic Mass759.887 Da
Topological Polar Surface Area332.000 Ų
Heavy Atom Count47
Formal Charge0
Complexity1430.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count5
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Jin Jing-Hao, Zhou Xue, Liu Wang, Zhang Zi-Hui, Huang Shen-Xin, Zhao Wen-Jing, Chen Xiao-Ren.  (2022)  Influence of affinity tags and tobacco PR1a signal peptide on detection, purification and bioactivity analyses of the small oomycete apoplastic effectors.  BIOTECHNOLOGY LETTERS,  45  (1): (115-124).  [PMID:36450976] [10.1007/s10529-022-03324-0]
2. Jingge Chen, Quanliang Cao, Xiaotao Han.  (2020)  Smart water-based ferrofluid with stable state transition property: Preparation and its application in anionic dye removal.  Journal of Cleaner Production,      [PMID:] [10.1016/j.jclepro.2020.125003]
3. Yanlei Hu, Liang Liu, Juan Yu, Zhiguo Wang, Yimin Fan.  (2020)  Preparation of Silk Nanowhisker-Composited Amphoteric Cellulose/Chitin Nanofiber Membranes.  BIOMACROMOLECULES,      [PMID:32212687] [10.1021/acs.biomac.0c00223]
4. Yanlei Hu, Liang Liu, Juan Yu, Zhiguo Wang, Yimin Fan.  (2020)  Preparation of Natural Multicompatible Silk Nanofibers by Green Deep Eutectic Solvent Treatment.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.9b07668]
5. Xin Zhao, Qing-Da An, Zuo-Yi Xiao, Shang-Ru Zhai, Zhan Shi.  (2018)  Seaweed-derived multifunctional nitrogen/cobalt-codoped carbonaceous beads for relatively high-efficient peroxymonosulfate activation for organic pollutants degradation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2018.07.171]
6. Cao Fengmei, Liu Haiteng, Wu Fengchang, Lu Shaoyong.  (2016)  Automated Determination of Chromium (VI) in Tannery Effluent Using Flow Injection Analysis with an Optical Flow Cell and Detector.  WATER AIR AND SOIL POLLUTION,  228  (1): (1-10).  [PMID:] [10.1007/s11270-016-3162-y]
7. Huimin Ruan, Changmeng Guo, Hongwei Yu, Jiangnan Shen, Congjie Gao, Arcadio Sotto, Bart Van der Bruggen.  (2016)  Fabrication of a MIL-53(Al) Nanocomposite Membrane and Potential Application in Desalination of Dye Solutions.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.6b03201]
8. Sun Yuxuan, Zhang Wang, Gu Junnan, Xia Liangyu, Cao Yinghao, Zhu Xinhui, Wen Hao, Ouyang Shaowei, Liu Ruiqi, Li Jialong, Jiang Zhenxing, Cheng Denglong, Lv Yiliang, Han Xiaotao, Qiu Wu, Cai Kailin, Song Enmin, Cao Quanliang, Li Liang.  (2024)  Magnetically driven capsules with multimodal response and multifunctionality for biomedical applications.  Nature Communications,  15  (1): (1-14).  [PMID:38424039] [10.1038/s41467-024-46046-9]
9. Ke Ning, Junzhi Li, Xiaoyan Yang, Yuanyuan Xie, Rong Pan, Wei Sun, Ling Yu.  (2024)  Microfluidic device-assisted 3D cell spheroids isolation, staining and embedding.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.111458]
10. Chang-Wei Zhang, Jian-Zhong Ye, Xing-Ying Xue, Wen-Jun Li, Hong-Xia Chen, Cheng-Zhang Wang.  (2025)  Green and Sustainable Production of Baphicacanthus cusia Extracts and Their Dyeing Effect and Wound-Healing Ability.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.5c06832]
11. Muhammad Muneeb Ahmad, Areena Fatima, Yunyun Ma, Munzar Badshah, Xiaoqin Ma, Zhaowei Qu, Lulu Huang, Lin Zhang, Vadivel Saravanan, Quansheng Xing, Zhaoyan Wang, Qiaosheng Pu.  (2026)  A robust Ti3C2Tx/alginate hydrogel reinforced with wheat straw cellulose microfibers (CMFs) for highly durable solar-driven water evaporation and desalination.  Sustainable Materials and Technologies,      [PMID:] [10.1016/j.susmat.2026.e01924]
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