Prednisolone disodium phosphate - ≥98%(HPLC) , Glucocorticoid receptor agonist, CAS No.125-02-0, Glucocorticoid receptor agonist

CAS: 125-02-0 Cat. No.: D155760 Peso molecular: 484.39 Número EC: 204-722-9 PubChem CID: 441409

GRADE & PURITY ≥98%(HPLC)

Synonyms

2-Chloro-4-pyridinylboronic acid, >=95.0% | D3918 | 11.BETA.,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 21-(DISODIUM PHOSPHATE | 11beta,17alpha-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate disodium | Inflamase Forte | Optival | Pediapred | Polypre

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

2-Chloro-4-pyridinylboronic acid, >=95.0% | D3918 | 11.BETA., 17, 21-TRIHYDROXYPREGNA-1, 4-DIENE-3, 20-DIONE 21-(DISODIUM PHOSPHATE | 11beta, 17alpha-dihydroxy-3, 20-dioxopregna-1, 4-dien-21-yl phosphate disodium | Inflamase Forte | Optival | Pediapred | Polypre

Especificaciones y pureza

≥98%(HPLC)

Mecanismos bioquímicos y fisiológicos

Water-soluble glucocorticoid. Anti-inflammatory agent. Orally active. Active in vitro and in vivo .

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

AGONIST

Mecanismo de acción

Glucocorticoid receptor agonist

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%(HPLC)

Nombres e identificadores

• Pubchem Sid: 504758766
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504758766
• Sonrisas canónicas: CC12CC(C3C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+].[Na+]
• IUPAC Name: disodium;[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
• InChIKey: VJZLQIPZNBPASX-OJJGEMKLSA-L
• INCHI: 1S/C21H29O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14-,15-,16-,18+,19-,20-,21-;;/m0../s1
• Isómeros SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=C[C@]34C)O.[Na+].[Na+]
• RTECS: TU4153300
• PubChem CID: 441409
• Peso molecular: 484.39
• Reaxy-Rn: 4795229

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Steroids and steroid derivatives
      • Subclass Pregnane steroids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Steroids and steroid derivatives
• Subclass: Pregnane steroids
• Intermediate Tree Nodes: Not available
• Direct Parent: Gluco/mineralocorticoids, progestogins and derivatives
• Alternative Parents: 20-oxosteroids 3-oxo delta-1,4-steroids 17-hydroxysteroids 11-beta-hydroxysteroids Delta-1,4-steroids Glycerone phosphates Alkyl phosphates Tertiary alcohols Alpha-hydroxy ketones Secondary alcohols Cyclic ketones Cyclic alcohols and derivatives Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Progestogin-skeleton - 20-oxosteroid - 3-oxo-delta-1,4-steroid - 3-oxosteroid - Hydroxysteroid - Oxosteroid - 11-beta-hydroxysteroid - 17-hydroxysteroid - 11-hydroxysteroid - Delta-1,4-steroid - Glycerone phosphate - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Cyclic alcohol - Alpha-hydroxy ketone - Tertiary alcohol - Cyclic ketone - Ketone - Secondary alcohol - Organic alkali metal salt - Organic oxide - Organic salt - Organooxygen compound - Organic oxygen compound - Organic sodium salt - Hydrocarbon derivative - Carbonyl group - Alcohol - Aliphatic homopolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Rotación específica [α]: 99° (C=1,pH 7.0 Buffer sol.)
• Peso molecular: 484.400 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 484.124 Da
• Monoisotopic Mass: 484.124 Da
• Topological Polar Surface Area: 147.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 878.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 7
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Referencias

1. Ruo-Yun Zhang, Wei Yue, Yang Xuan, Long Qi, Lin-Lin Guo, Zhen-Zhen Zhu, Ming Yang, Zhang-Jie Pu, Guo-Qiang Li, Xin-Yi Mao, Ding Zhou, Zhao-Wei Zhang.  (2026)  Injectable anti-inflammatory nanofiber hydrogel reprograms immunosuppressive tumor microenvironment via cascade-amplified immunogenic cell death.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.173232]