GRADE & PURITYBioReagent?BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility.Native?Native grade — protein/biomolecule in its natural (non-recombinant, non-denatured) form. Use when native structure and activity are required.≥95%(SDS-PAGE)from Human plasma; Pre-lyophilization Protein Concentration: See COA
BioReagent, Native, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA BioReagent,Native for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Purified from fresh frozen human plasma. Human Prekallikrein is a single chain gamma globulin glycoprotein that participates in the early phase of contact activation, kinin formation and fibrinolysis. Prekallikrein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Activity is determined via clotting assay.
Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
Extinction Coefficient (1%) =11.7
Molecular Weight = 86,000 daltons
The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.
Specifications
Product Name
Prekallikrein (PK), CAS No.9055-02-1
Grado
BioReagent, Native
Especificaciones y pureza
BioReagent, Native, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA
Mecanismos bioquímicos y fisiológicos
Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the ren
from Human plasma; Pre-lyophilization Protein Concentration: See COA
Reconstitución
We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C
Enviado en
Wet ice
Estabilidad y almacenamiento
Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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