Primidone - Moligand™, 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.125-33-7, Sodium channel alpha subunit blocker

CAS: 125-33-7 Cat. No.: P408422 Peso molecular: 218.25 Beilstein Registry Number: 24(5)102 Número EC: 204-737-0

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

NCI-C56360 | 5-​ethyldihydro-​5-​phenyl-4,​6(1H,​5H)​-​pyrimidinedione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Primidone Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥100%

Specifications

Sinónimos

NCI-C56360 | 5-​ethyldihydro-​5-​phenyl-4, ​6(1H, ​5H)​-​pyrimidinedione

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

CHANNEL BLOCKER, POSITIVE ALLOSTERIC MODULATOR

Mecanismo de acción

Sodium channel alpha subunit blocker

Propiedades del producto

• ALogP: 0.9

Nombres e identificadores

• Isómeros SMILES: CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
• RTECS: UV9100000
• Número ONU: 3249
• Grupo de embalaje: II
• Peso molecular: 218.25
• Beilstein: 24(5)102
• Reaxy-Rn: 218034
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=218034&ln=

Objetivos asociados (humanos)

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 (1 Activities)

Discover Target: TRPM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Índice de refracción: 1.53
• Punto de ebullición (°C): 520.70° C
• Punto de fusión (°C): 281°C

Referencias

1. Danni Cui, Huan He, Wenxiao Xie, Shanshan Yang, Ziwei Guo, Zhicheng Liao, Feng Liu, Chaochao Lai, Xiaomin Ren, Bin Huang, Xuejun Pan.  (2023)  Occurrence and cycle of dissolved iron mediated by humic acids resulting in continuous natural photodegradation of 17α-ethinylestradiol.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:38091802] [10.1016/j.jhazmat.2023.133155]

2. Xiuzhen Wei, Xiaoyan Bao, Jiawei Wu, Cuixia Li, Yingying Shi, Jinyuan Chen, Bosheng Lv, Baoku Zhu.  (2018)  Typical pharmaceutical molecule removal behavior from water by positively and negatively charged composite hollow fiber nanofiltration membranes.  RSC Advances,  8  (19): (10396-10408).  [PMID:35540449] [10.1039/C8RA00519B]