β-Propiolactone - Moligand™,≥98%(GC) , CAS No.57-57-8

CAS: 57-57-8 Cat. No.: P639527 Peso molecular: 72.06 Número EC: 200-340-1 PubChem CID: 2365
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(GC)
Synonyms
beta-Proprolactone | HYDRACRYLIC ACID, BETA-LACTONE | Oxetanone | 1,3-Propiolactone | BETRAPRONE | .beta.-Propanoic acid lactone | .beta.-Propriolactone | PROPIOLACTONE [ORANGE BOOK] | beta-Propanoic acid lactone | BRN 0001360 | DivK1c_001003 | Hydracryli
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
P639527-1ml
1
49,90US$
5ml
P639527-5ml
2
169,90US$
25ml
P639527-25ml
2
649,90US$
100ml
P639527-100ml
1
1.699,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™,≥98%(GC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
beta-Proprolactone | HYDRACRYLIC ACID, BETA-LACTONE | Oxetanone | 1, 3-Propiolactone | BETRAPRONE | .beta.-Propanoic acid lactone | .beta.-Propriolactone | PROPIOLACTONE [ORANGE BOOK] | beta-Propanoic acid lactone | BRN 0001360 | DivK1c_001003 | Hydracryli
Especificaciones y pureza
Moligand™, ≥98%(GC)
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Argon charged
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Pureza
≥98%(GC)
Nombres e identificadores
Sonrisas canónicasC1COC1=O
IUPAC Nameoxetan-2-one
InChIKeyVEZXCJBBBCKRPI-UHFFFAOYSA-N
INCHI1S/C3H4O2/c4-3-1-2-5-3/h1-2H2
Isómeros SMILES C1COC1=O
WGK Alemania 3
RTECS RQ7350000
PubChem CID 2365
Número ONU 2810
Grupo de embalaje I
Peso molecular 72.06

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseLactones
SubclassBeta propiolactones
Intermediate Tree Nodes Not available
Direct ParentBeta propiolactones
Alternative Parents Oxetanes  Carboxylic acid esters  Oxacyclic compounds  Monocarboxylic acids and derivatives  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents Beta_propiolactone - Oxetane - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as beta propiolactones. These are organic compounds containing a four-member lactone (a cyclic ester).
External Descriptors propan-3-olide
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeFechaArticulo
C2612613Certificate of AnalysisMar 04, 2026 P639527
C2612614Certificate of AnalysisMar 04, 2026 P639527
C2612770Certificate of AnalysisMar 04, 2026 P639527
C2612771Certificate of AnalysisMar 04, 2026 P639527
J2511585Certificate of AnalysisSep 25, 2025 P639527
J2511589Certificate of AnalysisSep 25, 2025 P639527
J2511591Certificate of AnalysisSep 25, 2025 P639527
A2513312Certificate of AnalysisMar 16, 2024 P639527
A2513313Certificate of AnalysisMar 16, 2024 P639527
C2404166Certificate of AnalysisMar 16, 2024 P639527
E2513015Certificate of AnalysisMar 16, 2024 P639527
E2513017Certificate of AnalysisMar 16, 2024 P639527
C2404164Certificate of AnalysisMar 15, 2024 P639527
C2404165Certificate of AnalysisMar 15, 2024 P639527
C2421002Certificate of AnalysisMar 15, 2024 P639527

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Propiedades químicas y físicas
SolubilidadSoluble in water and miscible in ethanol.
SensibilidadHeat sensitive;Moisture sensitive
Índice de refracción1.4131
Punto de inflamación (°F)158 °F
Punto de inflamación (°C)70℃
Punto de ebullición (°C)162.3°C
Punto de fusión (°C)-33.4°C
Peso molecular72.060 g/mol
XLogP3-0.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass72.0211 Da
Monoisotopic Mass72.0211 Da
Topological Polar Surface Area26.300 Ų
Heavy Atom Count5
Formal Charge0
Complexity57.900
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Yongheng Yin, Hui Xu, Chenyang Zhang, Weiyuan Hao, Qiying Xia, Shanmin Gao.  (2023)  Fabrication of polyamide/zwitterion functionalized mesoporous silica nanofiltration membrane with highly enhanced antifouling performance.  Journal of the Taiwan Institute of Chemical Engineers,      [PMID:] [10.1016/j.jtice.2023.104892]
2. Ting Wang, Jing Deng, Ruijin Ran, Wenqiang Shi, Yunxia Gao, Xiang Ren, Jun Cao, Ming Zhang.  (2022)  In-situ forming PEG-engineering hydrogels with anti-fouling characteristics as an artificial vitreous body.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.137486]
3. Jin Ma, Ke Kang, Yujia Zhang, Qiangying Yi, Zhongwei Gu.  (2018)  Detachable Polyzwitterion-Coated Ternary Nanoparticles Based on Peptide Dendritic Carbon Dots for Efficient Drug Delivery in Cancer Therapy.  ACS Applied Materials & Interfaces,      [PMID:30474366] [10.1021/acsami.8b17041]
4. Liping Zhu, Xiaodong Li, Changjian Song, Xiaohui Liu, Ying-Chiao Wang, Wenjun Zhang, Junfeng Fang.  (2017)  Cathode modification in planar hetero-junction perovskite solar cells through a small-molecule zwitterionic carboxylate.  ORGANIC ELECTRONICS,      [PMID:] [10.1016/j.orgel.2017.06.006]
5. Jin Ma, Ke Kang, Qiangying Yi, Zhirong Zhang, Zhongwei Gu.  (2016)  Multiple pH responsive zwitterionic micelles for stealth delivery of anticancer drugs.  RSC Advances,  (69): (64778-64790).  [PMID:] [10.1039/C6RA11645K]
6. Sixu Liu, Jingqi Li, Qingtian Cheng, Kangyi Duan, Zhan Wang, Shuang Yan, Shuaishuai Tian, Hairui Wang, Shaobin Wu, Xinkui Lei, Yu Yang, Ningning Ma.  (2024)  A Single-Step Method for Harvesting Influenza Viral Particles from MDCK Cell Culture Supernatant with High Yield and Effective Impurity Removal.  Viruses-Basel,  16  (5): (768).  [PMID:38793649] [10.3390/v16050768]
7. Mengdi Liang, Dulin Zuo, Feng Wang, Bei Zhang, Jingjing Tian, Xianchen Huang, Yuan Sun, Guanqiang Li, Xicheng Zhang, Gang Li.  (2025)  Drug-eluting vascular stents with surface modification of anticoagulation and pro-endothelialization.  BIOMACROMOLECULES,      [PMID:40990391] [10.1021/acs.biomac.5c01382]
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