≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
PROTAC RAR Degrader-1 comprises a IAP ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers ( SNIPER s)
Form:Solid
IC50& Target:cIAP1
| Sonrisas canónicas | CC(C)CC(C(=O)NCCOCCOCCOCC(=O)NCCCOC1=C(C=CC(=C1)C=CC(=O)C2=CC(=CC(=C2)C(C)(C)C)C(C)(C)C)C(=O)O)NC(=O)C(C(CC3=CC=CC=C3)N)O |
|---|---|
| IUPAC Name | 2-[3-[[2-[2-[2-[2-[[(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]propoxy]-4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid |
| InChIKey | ZAOSGDCLGNWLSI-ACALULJJSA-N |
| INCHI | 1S/C51H72N4O11/c1-34(2)27-42(55-48(60)46(58)41(52)28-35-13-10-9-11-14-35)47(59)54-20-22-63-23-24-64-25-26-65-33-45(57)53-19-12-21-66-44-29-36(15-17-40(44)49(61)62)16-18-43(56)37-30-38(50(3,4)5)32-39(31-37)51(6,7)8/h9-11,13-18,29-32,34,41-42,46,58H,12,19-28,33,52H2,1-8H3,(H,53,57)(H,54,59)(H,55,60)(H,61,62)/b18-16+/t41-,42+,46+/m1/s1 |
| Isómeros SMILES | CC(C)C[C@@H](C(=O)NCCOCCOCCOCC(=O)NCCCOC1=C(C=CC(=C1)/C=C/C(=O)C2=CC(=CC(=C2)C(C)(C)C)C(C)(C)C)C(=O)O)NC(=O)[C@H]([C@@H](CC3=CC=CC=C3)N)O |
| PubChem CID | 54764325 |
| Peso molecular | 917.14 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Clase | Peptidomimetics |
| Subclass | Hybrid peptides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Hybrid peptides |
| Alternative Parents | Retrochalcones Leucine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Beta amino acids and derivatives Amphetamines and derivatives Benzoic acids Phenylpropanes Phenol ethers Phenoxy compounds Styrenes Aryl ketones Benzoyl derivatives Alkyl aryl ethers Aralkylamines N-acyl amines Monosaccharides Enones Acryloyl compounds Amino acids Secondary carboxylic acid amides Secondary alcohols Monocarboxylic acids and derivatives Dialkyl ethers Carboxylic acids Monoalkylamines Hydrocarbon derivatives Organopnictogen compounds Organic oxides |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Hybrid peptide - Retrochalcone - Linear 1,3-diarylpropanoid - Leucine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Beta amino acid or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - Benzoic acid or derivatives - Benzoic acid - Phenylpropane - Phenoxy compound - Benzoyl - Phenol ether - Styrene - Aryl ketone - Alkyl aryl ether - Aralkylamine - Benzenoid - Monocyclic benzene moiety - N-acyl-amine - Monosaccharide - Fatty amide - Fatty acyl - Alpha,beta-unsaturated ketone - Acryloyl-group - Enone - Amino acid - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Secondary alcohol - Ketone - Dialkyl ether - Monocarboxylic acid or derivatives - Ether - Carboxylic acid derivative - Carboxylic acid - Primary amine - Alcohol - Organic oxide - Hydrocarbon derivative - Organopnictogen compound - Carbonyl group - Amine - Organic oxygen compound - Primary aliphatic amine - Organonitrogen compound - Organic nitrogen compound - Organooxygen compound - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond. |
| External Descriptors | Not available |
| Solubilidad | DMSO : ≥ 80 mg/mL (87.23 mM) |
|---|
