Puromycin aminonucleoside Ready Made Solution - 10 mg/mL in water , CAS No.58-60-6

CAS: 58-60-6 Cat. No.: P433000 Peso molecular: 294.31 Beilstein Registry Number: 93902 Número EC: 200-388-3

GRADE & PURITY 10 mg/mL in water

Synonyms

3'-amino-3'-deoxy-n(6),n(6)-dimethyladenosine | 0Q580U88V8 | Aminonucleoside | DTXSID7037264 | NSC 3056NSC 3056 | EINECS 200-388-3 | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL | AT25062 | Stylomycin ami

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

3'-amino-3'-deoxy-n(6), n(6)-dimethyladenosine | 0Q580U88V8 | Aminonucleoside | DTXSID7037264 | NSC 3056NSC 3056 | EINECS 200-388-3 | (2R, 3R, 4S, 5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL | AT25062 | Stylomycin ami

Especificaciones y pureza

10 mg/mL in water

Mecanismos bioquímicos y fisiológicos

Puromycin aminonucleoside is an aminonucleoside derivative of the known antibiotic puromycin. Puromycin aminonucleoside has been used in nephrology research, studying focal and segmental glomerulosclerosis, and in the induction of nephrosis in rats. Rats

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O
• IUPAC Name: (2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol
• InChIKey: RYSMHWILUNYBFW-GRIPGOBMSA-N
• INCHI: 1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7-,9-,12-/m1/s1
• Isómeros SMILES: CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)N)O
• WGK Alemania: 3
• Peso molecular: 294.31
• Beilstein: 93902
• Reaxy-Rn: 14439847
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14439847&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleosides
      • Subclass Purine 3'-deoxyribonucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleosides
• Subclass: Purine 3'-deoxyribonucleosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine 3'-deoxyribonucleosides
• Alternative Parents: 6-alkylaminopurines Glycosylamines Pentoses Dialkylarylamines Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Tetrahydrofurans 1,3-aminoalcohols Heteroaromatic compounds Secondary alcohols 1,2-aminoalcohols Oxacyclic compounds Azacyclic compounds Monoalkylamines Organopnictogen compounds Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine 3'-deoxyribonucleoside - 6-alkylaminopurine - N-glycosyl compound - Glycosyl compound - 6-aminopurine - Pentose monosaccharide - Imidazopyrimidine - Purine - Dialkylarylamine - Aminopyrimidine - Monosaccharide - Imidolactam - N-substituted imidazole - Pyrimidine - 1,3-aminoalcohol - Heteroaromatic compound - Imidazole - Tetrahydrofuran - Azole - 1,2-aminoalcohol - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Primary alcohol - Primary amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Alcohol - Primary aliphatic amine - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine 3'-deoxyribonucleosides. These are compounds consisting of a purine linked to a ribose which lacks a hydroxyl group at position 3.
• External Descriptors: adenosines - 3'-deoxyribonucleoside

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Trypanosoma cruzi (99888 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Peso molecular: 294.310 g/mol
• XLogP3: -0.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 294.144 Da
• Monoisotopic Mass: 294.144 Da
• Topological Polar Surface Area: 123.000 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 373.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Shijie Wang, Yujuan He, Lu Peng, Peng Jiang, Hongxia Wang, Hai-Bo Chang, Tong Lin.  (2025)  Source Dependence of Polyacrylonitrile Electrospun Nanofibers on Piezoelectric Response†.  Journal of Materials Chemistry A,      [PMID:] [10.1039/D5TA02608C]