Pyrvinium Pamoate - ≥98% , CAS No.3546-41-6

CAS: 3546-41-6 Cat. No.: P342988 Peso molecular: 1151.39 Número EC: 222-596-3 PubChem CID: 54680693

GRADE & PURITY ≥98%

Synonyms

Povan (TN) | Vanquil | .ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-3'-ISOPROPOXY-O-TOLUANILIDE | Pyrvinium embonate | Pyrvinium pamoate | Dipyrivinium Pamoate | Pyrviniumpamoate | SR-01000872694 | Terzolin | Z2196311755 | bis{6-(dimethylamino)-2-[(E)-2-(2,5-dimethy

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

Povan (TN) | Vanquil | .ALPHA., .ALPHA., .ALPHA.-TRIFLUORO-3'-ISOPROPOXY-O-TOLUANILIDE | Pyrvinium embonate | Pyrvinium pamoate | Dipyrivinium Pamoate | Pyrviniumpamoate | SR-01000872694 | Terzolin | Z2196311755 | bis{6-(dimethylamino)-2-[(E)-2-(2, 5-dimethy

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Enpovidam is an effective androgen receptor inhibitor. Androgen receptor (AR) is a nuclear hormone receptor / transcription factor, which exists in the cytoplasm and can be activated by testosterone and dihydrotestosterone. AR inhibitors have potential th

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: CC1=CC(=C(N1C2=CC=CC=C2)C)C=CC3=[N+](C4=C(C=C3)C=C(C=C4)N(C)C)C.CC1=CC(=C(N1C2=CC=CC=C2)C)C=CC3=[N+](C4=C(C=C3)C=C(C=C4)N(C)C)C.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)[O-])[O-])C(=O)O
• IUPAC Name: 3-carboxy-1-[(3-carboxy-2-oxidonaphthalen-1-yl)methyl]naphthalen-2-olate;2-[(E)-2-(2,5-dimethyl-1-phenylpyrrol-3-yl)ethenyl]-N,N,1-trimethylquinolin-1-ium-6-amine
• InChIKey: OOPDAHSJBRZRPH-UHFFFAOYSA-L
• INCHI: 1S/2C26H28N3.C23H16O6/c2*1-19-17-21(20(2)29(19)24-9-7-6-8-10-24)11-13-23-14-12-22-18-25(27(3)4)15-16-26(22)28(23)5;24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h2*6-18H,1-5H3;1-10,24-25H,11H2,(H,26,27)(H,28,29)/q2*+1;/p-2
• Isómeros SMILES: CC1=CC(=C(N1C2=CC=CC=C2)C)/C=C/C3=[N+](C4=C(C=C(C=C4)N(C)C)C=C3)C.CC1=CC(=C(N1C2=CC=CC=C2)C)/C=C/C3=[N+](C4=C(C=C(C=C4)N(C)C)C=C3)C.C1=CC=C2C(=C(C(=CC2=C1)C(=O)O)[O-])CC3=C(C(=CC4=CC=CC=C34)C(=O)O)[O-]
• PubChem CID: 54680693
• Peso molecular: 1151.39

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Naphthalenes
      • Subclass Naphthalenecarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Naphthalenes
• Subclass: Naphthalenecarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthalenecarboxylic acids
• Alternative Parents: Phenylpyrroles Aminoquinolines and derivatives Dialkylarylamines Phenoxides Pyridinium derivatives Dicarboxylic acids and derivatives Vinylogous acids Heteroaromatic compounds Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organic salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: 2-naphthalenecarboxylic acid - Aminoquinoline - 1-phenylpyrrole - Quinoline - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Phenoxide - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - Pyridine - Pyridinium - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Vinylogous acid - Tertiary amine - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Carboxylic acid - Amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic salt - Organic oxide - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as naphthalenecarboxylic acids. These are compounds containing a naphthalene moiety, which bears a carboxylic acid group one or more positions. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Candida albicans (78123 Activities)

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BHK-21 (725 Activities)

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LLC-MK2 (227 Activities)

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Fumarate reductase (7 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Moisture & Light sensitive
• Punto de fusión (°C): 215-223° C
• Peso molecular: 1151.400 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 12
• Exact Mass: 1150.54 Da
• Monoisotopic Mass: 1150.54 Da
• Topological Polar Surface Area: 145.000 Ų
• Heavy Atom Count: 87
• Formal Charge: 0
• Complexity: 1120.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 3

XLogP3

Referencias

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2. Wei Song, Yu Xiao.  (2021)  Sequential drug delivery of vancomycin and rhBMP-2 via pore-closed PLGA microparticles embedded photo-crosslinked chitosan hydrogel for enhanced osteointegration.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:33838200] [10.1016/j.ijbiomac.2021.03.181]

3. Yingnan Liu, Yaqing Xiao, Min Yu, Yuanyuan Cao, Yalan Zhang, Taotao Zhe, Hui Zhang, Li Wang.  (2020)  Antimonene Quantum Dots as an Emerging Fluorescent Nanoprobe for the pH-Mediated Dual-Channel Detection of Tetracyclines.  Small,  16  (42): (2003429).  [PMID:32996281] [10.1002/smll.202003429]

4. Yinyin Liu, Zehao Li, Shuiyang Zou, Chunbo Lu, Yao Xiao, Hu Bai, Xiaoli Zhang, Haibo Mu, Xiuyun Zhang, Jinyou Duan.  (2020)  Hyaluronic acid-coated ZIF-8 for the treatment of pneumonia caused by methicillin-resistant Staphylococcus aureus.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:32224180] [10.1016/j.ijbiomac.2020.03.187]

5. Xia Kaixin, Zhang Guowen, Li Song, Gong Deming.  (2017)  Groove Binding of Vanillin and Ethyl Vanillin to Calf Thymus DNA.  JOURNAL OF FLUORESCENCE,  27  (5): (1815-1828).  [PMID:28547116] [10.1007/s10895-017-2119-x]

6. Lin Jiang, Yaping Ding, Feng Jiang, Li Li, Fan Mo.  (2014)  Electrodeposited nitrogen-doped graphene/carbon nanotubes nanocomposite as enhancer for simultaneous and sensitive voltammetric determination of caffeine and vanillin.  ANALYTICA CHIMICA ACTA,      [PMID:24909770] [10.1016/j.aca.2014.05.010]

7. Wang Qiuyang, Wang Lanlan, Liu Xinyun, Chen Haojun, Wang Xucai, Wang Peng, Wang Weijun, Jiang Qing.  (2025)  A pH-responsive magnetic-controlled nanocomposite for precise and efficient vancomycin delivery in treating prosthetic joint infections.  Advanced Composites and Hybrid Materials,  8  (1): (1-17).  [PMID:] [10.1007/s42114-024-01079-y]

8. Kuiyuan Cao, Fang Yang, He Wan, Xixin Duan, Junyou Shi, Zhong Sun.  (2025)  A selective oxidative depolymerization of larch lignin to ethyl vanillate by multifunctional catalysts combining alkaline ionic liquid and polyoxometalates with hydrogen peroxide.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39793812] [10.1016/j.ijbiomac.2025.139642]

9. Zhiyuan Hu, Jie Shan, Xu Jin, Weijie Sun, Liang Cheng, Xu-Lin Chen, Xianwen Wang.  (2024)  Nanoarchitectonics of in Situ Antibiotic-Releasing Acicular Nanozymes for Targeting and Inducing Cuproptosis-like Death to Eliminate Drug-Resistant Bacteria.  ACS Nano,      [PMID:39169538] [10.1021/acsnano.4c06565]

10. Yujue Feng, Hongyuan Guo, Guojuan Zhang, Yingchun Zhu, Suozhu Wu.  (2024)  Picomole determination of vanillin in infant formula by molecularly imprinted polypyrrole nanowires/reduced graphene oxide-based electrochemical sensor.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.111248]

11. Yanna Zhao, Yingying Zhang, Xiaowei Bai, Yuqi Wang, Yiqing Li, Shuai Yang.  (2024)  Sustainable poly(imide-imide) vitrimer based on multiple dynamic covalent bonds.  JOURNAL OF APPLIED POLYMER SCIENCE,  141  (48): (e56281).  [PMID:] [10.1002/app.56281]

12. Wenwen Cao, Anli Qin, Wenqian Zhu, Chaohai Pang, Zhongsheng Yi, Xionghui Ma, Shuhuai Li, Jianping Li.  (2024)  In Situ growth of high-crystallinity MOF@CTF core-shell hybrid heterostructures and their application in photoelectrochemical sensing of vancomycin.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2024.104963]

13. Lin Zhang, Xiaoling Lu, Hao Li, Hongjie Chen, Qi Yin, Xuehan Hu, Kang Yang, Fang Yang, Liya Chen, Zeng Yang, You Long, Chao Shen, Bo Yao, Chenghong Huang.  (2025)  Crystallization of Vanillin Isomers in Carboxymethyl Chitosan Gels.  Gels,  11  (4): (285).  [PMID:40277721] [10.3390/gels11040285]

14. Qian Jiang, Shuguang Xu, Zuzhi Li, Xingjie Guo, Rui Zhang, Zhicheng Jiang, Bi Shi.  (2025)  Synergistic SiO2@NC core-shell nanosphere enhances catalytic hydrogenation of lignin-derived aromatic aldehydes.  GREEN CHEMISTRY,      [PMID:] [10.1039/D5GC00857C]

15. Xipeng Chen, Yuanpei Cheng, Yongbo Li, Ze Tan, Han Wu.  (2025)  3D-printed vancomycin-eluting PGCL/MXene bifunctional scaffold for management of infected bone defects.  Materials Today Bio,      [PMID:40475861] [10.1016/j.mtbio.2025.101847]

16. Xue Yang, Yao Pan, NaiSheng Wu, Huiqing Ding, Fangling Wu, Li Ding, Chuan-Fan Ding.  (2026)  Unraveling Chiral Recognition for Ofloxacin Enantiomers: An IMS-MS Study Enabled by Noncovalent Complexation and Theoretical Modeling.  ANALYTICAL CHEMISTRY,      [PMID:41589714] [10.1021/acs.analchem.5c07410]