for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Quazinone (Ro 13-6438) is a selective phosphodiesterase (PDE) inhibitor, and a novel cardiotonic agent with vasodilating properties. It has been reported to inhibit myocardial PDE activity and elevate levels of intracellular cyclic AMP (cAMP), causing a positive inotropic response in isolated guina pig papillary muscle. It has been shown to increase the upstroke velocity, overshoot, and duration of slow action potentials in a concentration-dependent fashion in partially depolarized papillary muscles.
This compound belongs to the class of organic compounds known as quinazolines. These are compounds containing a quinazoline moiety, which is made up of two fused six-member aromatic rings, a benzene ring and a pyrimidine ring.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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