Rat ghrelin-28 - Moligand™, ≥95% , Agonist of ghrelin receptor, CAS No.258338-12-4, Agonist of ghrelin receptor

CAS: 258338-12-4 Cat. No.: G111460 Peso molecular: 3314.8 PubChem CID: 44134734

GRADE & PURITY Moligand™, ≥95%

Synonyms

GHRELIN, RAT | GSSFLSPEHQKAQQRKESKKPPAKLQPR | DTXSID70657540 | LS-15550 | MFCD07366495 | (Ser-3 = Ser(n-octanoyl)) | C147H245N45O42 | Glycylseryl-N-octanoylserylphenylalanylleucylserylprolyl-alpha-glutamylhistidylglutaminyllysylalanylglutaminylglutaminyla

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

The amino acid sequence：Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg

Specifications

Sinónimos

GHRELIN, RAT | GSSFLSPEHQKAQQRKESKKPPAKLQPR | DTXSID70657540 | LS-15550 | MFCD07366495 | (Ser-3 = Ser(n-octanoyl)) | C147H245N45O42 | Glycylseryl-N-octanoylserylphenylalanylleucylserylprolyl-alpha-glutamylhistidylglutaminyllysylalanylglutaminylglutaminyla

Especificaciones y pureza

Moligand™, ≥95%

Mecanismos bioquímicos y fisiológicos

Endogenous agonist peptide for the ghrelin (GHS) receptor. Stimulates release of growth hormone from the pituitary gland and regulates feeding, growth and energy production.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of ghrelin receptor

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Isómeros SMILES: CCCCCCCC(=O)N(C(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)N2CCCC2C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CNC=N3)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)N6CCCC6C(=O)NC(CCCNC(=N)N)C(=O)O)C(=O)C(CO)NC(=O)CN
• PubChem CID: 44134734
• Peso molecular: 3314.8

Objetivos asociados (humanos)

GHSR Tclin Growth hormone secretagogue receptor type 1 (0 Activities)

Discover Target: GHSR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Referencias

1. Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun.  (2023)  Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis.  Molecular Medicine Reports,  28  (3): (1-14).  [PMID:37449526] [10.3892/mmr.2023.13050]

2. Shi-shi Liao, Le-le Zhang, Yi-guo Zhang, Jie Luo, Tulanisa Kadier, Ke Ding, Rong Chen, Qing-tao Meng.  (2024)  Ghrelin alleviates intestinal ischemia–reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway.  FASEB JOURNAL,  38  (11): (e23681).  [PMID:38814725] [10.1096/fj.202302155RRR]

3. He Chengjian, Song Xiaojing, Zhu Zigui, Xiao Yan, Chen Jiacheng, Yao Hongyi, Xie Rongjun.  (2024)  Ghrelin may protect against vascular endothelial injury in Acute traumatic coagulopathy by mediating the RhoA/ROCK/MLC2 pathway.  JOURNAL OF THROMBOSIS AND THROMBOLYSIS,      [PMID:39179950] [10.1007/s11239-024-03029-3]