GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.High Performance?High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short.Fc tag?Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥90%(SDS-PAGE)See COA
Accession #
P21802
Protein Tag
C-hFc
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Measured by its ability to inhibit FGF acidic dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 110.5 ng/mL in the presence of 150ng/mL FGF1 (rp170413). Immobilized Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) at 1.0 μg/mL can bind Bemarituzumab (anti-FGFR2) (Ab170514) with the EC50 of 22.7 ng/mL.
ActiBioPure™, Animal Free, Bioactive, Carrier Free, Fc tag, High Performance, PBS Only
Especificaciones y pureza
Animal Free, Carrier Free, Bioactive, ActiBioPure™, High Performance, Fc tag, PBS Only, ≥90%(SDS-PAGE), See COA
Mecanismos bioquímicos y fisiológicos
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healin
Bioactividad
Measured by its ability to inhibit FGF acidic dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 110.5 ng/mL in the presence of 150ng/mL FGF1 (rp170413). Immobilized Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) at 1.0 μg/mL can bind Bemarituzumab (anti-FGFR2) (Ab170514) with the EC50 of 22.7 ng/mL.
90.2 kDa, under reducing conditions; 115.4 & 220.7 kDa, under non-reducing conditions.
Tipo de molécula
Protein
Almacenamiento y envío
Concentración
See COA
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20℃ for 12 months. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) - Bioactivity Measured by its ability to inhibit FGF acidic dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 110.5 ng/mL in the presence of 150 ng/mL FGF1 (rp170413).
Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) - ELISA Immobilized Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) at 1.0 μg/mL can bind Bemarituzumab (anti-FGFR2) (Ab170514) with the EC50 of 22.7 ng/mL.
Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) - SDS-PAGE 3 μg/lane of Recombinant Human FGFR2 alpha (IIIb) Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 90.2 kDa under reducing conditions and 115.4 & 220.7 kDa under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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