GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥90%(SDS-PAGE)See COA
Carrier Free,His-Tag,≥90%(SDS-PAGE),See COA Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications
Product Name
Recombinant Human HIF-2 alpha Protein
Sinónimos
Endothelial PAS domain-containing protein 1 | EPAS-1 | Basic-helix-loop-helix-PAS protein MOP2 | Class E basic helix-loop-helix protein 73 (bHLHe73) | HIF-1-alpha-like factor (HLF) | Hypoxia-inducible factor 2-alpha (HIF-2-alpha | HIF2-alpha) | Member of
Grado
Carrier Free, His Tag
Especificaciones y pureza
Carrier Free, His-Tag, ≥90%(SDS-PAGE), See COA
Mecanismos bioquímicos y fisiológicos
Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vasc
36.7 & 77.9 kDa, under reducing conditions; 35.6 & 68.4-83.2 kDa, under non-reducing conditions.
Tipo de molécula
Protein
Almacenamiento y envío
Concentración
See COA
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Imágenes
Recombinant Human HIF-2 alpha Protein (rp186522) - SDS-PAGE 3 μg/lane of Recombinant Human HIF-2 alpha Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 36.7 & 77.9 kDa under reducing conditions and 35.6 & 68.4-83.2 kDa under non-reducing conditions. HIF-2α's C-terminal transactivation domain (CTAD, residues 543-870) recruits transcriptional coactivators to activate target gene transcription and may adopt multiple conformations under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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