GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.≥95%(SDS-PAGE)
Accession #
Q14116
Protein Tag
No tag
Expression system
E. coli
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp186564) with the EC50 of 30.0 ng/mL. Immobilized Recombinant IL-18 protein (rp186564) at 1.0 μg/mL can bind Camoteskimab (anti-IL-18) (Ab182692) with the EC50 of 400.2 ng/mL.
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The com
Bioactividad
Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp186564) with the EC50 of 30.0 ng/mL. Immobilized Recombinant IL-18 protein (rp186564) at 1.0 μg/mL can bind Camoteskimab (anti-IL-18) (Ab182692) with the EC50 of 400.2 ng/mL.
15.7 kDa, under reducing conditions; 15.7 kDa, under non-reducing conditions.
Tipo de molécula
Protein
Almacenamiento y envío
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Imágenes
Recombinant Human IL-18 Protein (rp186564) - Binding Activity Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp186564) with the EC
₅₀
of 30.0 ng/mL.
Recombinant Human IL-18 Protein (rp186564) - Binding Activity Immobilized Recombinant IL-18 protein (rp186564) at 1.0 μg/mL can bind Camoteskimab (anti-IL-18) (Ab182692) with the EC
₅₀
of 400.2 ng/mL.
Recombinant Human IL-18 Protein (rp186564) - SDS-PAGE 3 μg/lane of Recombinant Human IL-18 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 15.7 kDa.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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