Recombinant Human IL-6 & IL-6R alpha Protein

Cat. No.: rp232517
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE) expressed in HEK293; See COA
Accession #
P08887,P05231
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human IL-6 & IL-6R alpha Protein (rp232517) at 2.0 μg/mL can bind Recombinant Human gp130 Protein (rp183628) with the EC50 of 25.1 ng/mL.
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
10μg
rp232517-10μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
139,90US$
50μg
rp232517-50μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
399,90US$
100μg
rp232517-100μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
629,90US$
1mg
rp232517-1mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
3.149,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Animal Free,Carrier Free,Bioactive,ActiBioPure™,His Tag,≥95%(SDS-PAGE),expressed in HEK293; See COA ActiBioPure™,Animal Free,Bioactive,Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
Recombinant Human IL-6 & IL-6R alpha Protein
Sinónimos
Interleukin 6/Interleukin 6 Receptor alpha Complex | Interleukin 6 & Interleukin 6 Receptor alpha Complex
Grado
ActiBioPure™, Animal Free, Bioactive, Carrier Free, His Tag
Especificaciones y pureza
Animal Free, Carrier Free, Bioactive, ActiBioPure™, His Tag, ≥95%(SDS-PAGE), expressed in HEK293; See COA
Mecanismos bioquímicos y fisiológicos
Interleukin-6 (IL-6) is a pleiotropic, alpha -helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human I
Bioactividad
Immobilized Recombinant Human IL-6 & IL-6R alpha Protein (rp232517) at 2.0 μg/mL can bind Recombinant Human gp130 Protein (rp183628) with the EC50 of 25.1 ng/mL.
Concentración de endotoxinas
<1.0 EU/μg
Aminoácidos
IL-6R (1-358 aa) & IL-6 (30-212 aa)
Secuencia
MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDGGGSGGGSGGGSVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQMHHHHHH
Número de adhesión
Peso molecular previsto
60.3 kDa
SDS-PAGE
68.2-96.5 kDa; under reducing conditions; 68.2-96.5 kDa; under non-reducing conditions.
Tipo de molécula
Protein
Almacenamiento y envío
Concentración
expressed in HEK293; See COA
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20℃ for 12 months. Upon reconstitution; it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Recombinant Human IL-6/IL-6R alpha Protein (rp232517) - ELISA 
Immobilized Recombinant Human IL-6/IL-6R alpha Protein (rp232517) at 2.0 μg/mL can bind Recombinant Human gp130 Protein (rp183628) with the EC₅₀ of 25.1 ng/mL.
Recombinant Human IL-6/IL-6R alpha Protein (rp232517) - SDS-PAGE 
3 μg/lane of Recombinant Human IL-6/IL-6R alpha Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 68.2-96.5 kDa.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ26F0434564Certificate of AnalysisApr 24, 2026 rp232517
ZJ26F0434563Certificate of AnalysisApr 24, 2026 rp232517
ZJ26F0434562Certificate of AnalysisApr 24, 2026 rp232517
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