GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥90%(SDS-PAGE)
Accession #
P43489
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind BMS-986178 (anti-CD134) (Ab209739) with the EC50 of 38.0 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Ivuxolimab (anti-CD134) (Ab182815) with the EC50 of 32.7 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Tavolixizumab (anti-CD134) (Ab182830) with the EC50 of 41.2 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Cudarolimab (anti-CD134) (Ab182885) with the EC50 of 112.0 ng/mL.
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. Th
Bioactividad
Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind BMS-986178 (anti-CD134) (Ab209739) with the EC50 of 38.0 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Ivuxolimab (anti-CD134) (Ab182815) with the EC50 of 32.7 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Tavolixizumab (anti-CD134) (Ab182830) with the EC50 of 41.2 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Cudarolimab (anti-CD134) (Ab182885) with the EC50 of 112.0 ng/mL.
31.6- 49.3 kDa, under reducing conditions; 28.9-49.9 kDa, under non-reducing conditions
Tipo de molécula
Protein
Almacenamiento y envío
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Imágenes
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind BMS-986178 (anti-CD134) (Ab209739) with the EC₅₀ of 38.0 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Ivuxolimab (anti-CD134) (Ab182815) with the EC₅₀ of 32.7 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Tavolixizumab (anti-CD134) (Ab182830) with the EC₅₀ of 41.2 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Cudarolimab (anti-CD134) (Ab182885) with the EC₅₀ of 112.0 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - SDS-PAGE 3 μg/lane of Recombinant Human OX40/TNFRSF4 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 31.6- 49.3 kDa under reducing conditions and 28.9-49.9 kDa under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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