GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥95%(SDS-PAGE)
Sin portador, ≥95%(SDS-PAGE) Carrier Free,PBS Only for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Conservar a -20°C,Evitar la congelación y descongelación repetidas Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Función de la proteína: Se une al receptor patched (PTC), que funciona en asociación con smoothened (SMO), para activar la transcripción de genes diana. En ausencia de SHH, PTC reprime la actividad de señalización constitutiva de SMO. También regula otra diana, el oncogén gli. Señal intercelular esencial para una variedad de eventos de patrón durante el desarrollo: señal producida por la notocorda que induce el destino celular ventral en el tubo neural y los somitas, y la señal polarizadora para el patrón del eje anteroposterior de la yema del miembro en desarrollo. Muestra actividad inductora tanto de la placa del suelo como de la motoneurona. La concentración umbral de producto N necesaria para la inducción de la motoneurona es 5 veces inferior a la requerida para la inducción de la placa del suelo.
Specifications
Product Name
Proteína humana recombinante Sonic Hedgehog/Shh (C24II)
Sinónimos
HHG-1 | HLP3 | HPE3 | MCOPCB5 | MCOPCB5sonic hedgehog (Drosophila) homolog | Shh | ShhNC | SMMCI | HHG1 | SMMCIsonic hedgehog homolog (Drosophila) | sonic hedgehog homolog | sonic hedgehog protein | Sonic Hedgehog | TPT | TPTPS
19.3 kDa, under reducing conditions; 19.3 kDa, under non-reducing conditions
Tipo de molécula
Protein
Almacenamiento y envío
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Conservar a -20°C,Evitar la congelación y descongelación repetidas
Enviado en
Hielera + almohadillas de hielo
Estabilidad y almacenamiento
Conservar a -20°C durante 1 año. Evitar el ciclo de congelación/descongelación.
Imágenes
Recombinant Human Sonic Hedgehog/Shh (C24II) Protein - SDS-PAGE 3 μg/lane of Recombinant Human Sonic Hedgehog/Shh (C24II) Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 19.3 kDa.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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