GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥90%(SDS-PAGE)
Sin portador, ≥90%(SDS-PAGE) Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping
Conservar a -20°C,Evitar la congelación y descongelación repetidas Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
📋
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
SOX2 es un miembro de la subfamilia SOXB1 de factores de transcripción que interviene principalmente en la reprogramación de células somáticas en células madre pluripotentes inducidas. Ubicado en el cromosoma 3, el gen SOX2 codifica para una proteína con un dominio de activación transcripcional C-terminal y un dominio HMG de unión al ADN que contiene una señal de localización/exportación nuclear. SOX2 forma un complejo trimérico con OCT4 en el ADN y controla la expresión de varios genes implicados en el desarrollo embrionario y la pluripotencia, como YES1, FGF4, UTF1 y ZFP206. Las mutaciones en este gen se han asociado a la enfermedad ocular bilateral. Se han encontrado antígeno y anticuerpo SOX2 en líneas celulares y sueros de cáncer de pulmón microcítico. Sin embargo, ninguno de ellos existe en sueros normales, lo que sugiere que SOX2 podría ser una diana o marcador tumoral potencial.
Specifications
Product Name
Proteína SOX2 humana recombinante
Sinónimos
cb236 | Delta EF2a | Lcc | MCOPS3 | MGC148683 | MGC2413 | RGD1565646 | Sex determining region Y box 2 | ANOP3 | SOX 2 | Sox2 | SOX2_HUMAN | SRY (sex determining region Y) box 2 | SRY box containing gene 2 | SRY related HMG box 2 | SRY related HMG box gene
37.3 kDa, under reducing conditions; 37.3 kDa, under non-reducing conditions
Tipo de molécula
Protein
Almacenamiento y envío
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Conservar a -20°C,Evitar la congelación y descongelación repetidas
Enviado en
Hielera + almohadillas de hielo
Estabilidad y almacenamiento
Conservar a -20°C durante 1 año. Evitar el ciclo de congelación/descongelación.
Imágenes
Recombinant Human SOX2 Protein (rp156646) - SDS-PAGE 3 μg/lane of Recombinant Human SOX2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 37.3 kDa.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.
Shall we send you a message when we have discounts available?
Remind me later
Thank you! Please check your email inbox to confirm.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
ZJ24F0809455
