RN-1 dihydrochloride - ≥97% , CAS No.1781835-13-9

CAS: 1781835-13-9 Cat. No.: R276429 Peso molecular: 452.42 PubChem CID: 90488995

GRADE & PURITY ≥97%

Synonyms

1-(4-Methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethenonedihydrochloride

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

Specifications

Sinónimos

1-(4-Methylpiperazin-1-yl)-2-[[(1R, 2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethenonedihydrochloride

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

Potent, cell-permeable LSD-1 inhibitor (IC 50 = 70 nM). Selective for LSD-1 versus MAO-A (IC 50 = 0.51\xa0μM) and MAO-B (IC 50 = 2.79\xa0μM).\xa0Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥97%

Nombres e identificadores

• Sonrisas canónicas: CN1CCN(CC1)C(=O)CNC2CC2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl
• IUPAC Name: 1-(4-methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethanone;dihydrochloride
• InChIKey: WMHAFZOOUBPQRX-VSIGASKDSA-N
• INCHI: 1S/C23H29N3O2.2ClH/c1-25-11-13-26(14-12-25)23(27)16-24-22-15-21(22)19-7-9-20(10-8-19)28-17-18-5-3-2-4-6-18;;/h2-10,21-22,24H,11-17H2,1H3;2*1H/t21-,22+;;/m0../s1
• Isómeros SMILES: CN1CCN(CC1)C(=O)CN[C@@H]2C[C@H]2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl
• PubChem CID: 90488995
• Peso molecular: 452.42

Propiedades químicas y físicas

• Solubilidad: DMSO: 8 mg/mL Water: 8 mg/mL