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Roflupram（FFPM） - Moligand™, ≥98%(HPLC) , Inhibitor of phosphodiesterase 4B, CAS No.1093412-18-0, Inhibitor of phosphodiesterase 4B

CAS: 1093412-18-0 Cat. No.: R492367 Peso molecular: 314.32 PubChem CID: 25147798
COA
Roflupram（FFPM） - Moligand™, ≥98%(HPLC) CAS No(1093412-18-0) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
R492367-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
73,90US$
5mg
R492367-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
233,90US$
10mg
R492367-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
379,90US$
25mg
R492367-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
739,90US$
50mg
R492367-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.199,90US$
100mg
R492367-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.799,90US$
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Especificaciones y pureza
Moligand™, ≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Roflupram (FFPM) is an effective anti-inflammatory phosphodiesterase 4 (PDE4) inhibitor that can inhibit microglial inflammasome activation by enhancing autophagy. In BV-2 microglia, roflupram increased the level of microtubule associated protein 1 light
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Mecanismo de acción
Inhibitor of phosphodiesterase 4B
Pureza
≥98%(HPLC)
Nombres e identificadores
Sonrisas canónicasCC(C)CC(=O)C1=CC(=C(C=C1)OC(F)F)OC2CCOC2
IUPAC Name1-[4-(difluoromethoxy)-3-(oxolan-3-yloxy)phenyl]-3-methylbutan-1-one
InChIKeyIXURVUHDDXFYDR-UHFFFAOYSA-N
INCHI1S/C16H20F2O4/c1-10(2)7-13(19)11-3-4-14(22-16(17)18)15(8-11)21-12-5-6-20-9-12/h3-4,8,10,12,16H,5-7,9H2,1-2H3
Isómeros SMILES CC(C)CC(=O)C1=CC(=C(C=C1)OC(F)F)OC2CCOC2
PubChem CID 25147798
Peso molecular 314.32

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClaseOrganooxygen compounds
SubclassCarbonyl compounds
Intermediate Tree Nodes Ketones - Aryl ketones - Phenylketones
Direct ParentAlkyl-phenylketones
Alternative Parents Butyrophenones  Phenoxy compounds  Phenol ethers  Benzoyl derivatives  Aryl alkyl ketones  Alkyl aryl ethers  Oxolanes  Oxacyclic compounds  Dialkyl ethers  Organofluorides  Organic oxides  Hydrocarbon derivatives  Alkyl fluorides  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Alkyl-phenylketone - Butyrophenone - Phenoxy compound - Benzoyl - Aryl alkyl ketone - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Oxolane - Oxacycle - Organoheterocyclic compound - Dialkyl ether - Ether - Alkyl fluoride - Organic oxide - Hydrocarbon derivative - Alkyl halide - Organohalogen compound - Organofluoride - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE4B Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE7A Tclin Phosphodiesterase 7A (1104 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE9A Tchem Phosphodiesterase 9A (1131 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
PDE2A Phosphodiesterase 2A (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Peso molecular314.320 g/mol
XLogP33.800
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass314.133 Da
Monoisotopic Mass314.133 Da
Topological Polar Surface Area44.800 Ų
Heavy Atom Count22
Formal Charge0
Complexity362.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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