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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items Ropivacaine hydrochloride - ≥98% , Sodium channel alpha subunit blocker, CAS No.98717-15-8, Sodium channel alpha subunit blocker
Synonyms
MLS001401363 | NCGC00164597-02 | Phosphocholine (chloride calcium) | MFCD02102164 | Q27128599 | SCHEMBL236432 | (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride | ROPIVACAINE HYDROCHLORIDE ANHYDROUS | NC00358 | ROPIVACAINE HCl |
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is widely used for neuropathic pain management in vivo.
Specifications Sinónimos
MLS001401363 | NCGC00164597-02 | Phosphocholine (chloride calcium) | MFCD02102164 | Q27128599 | SCHEMBL236432 | (2S)-N-(2, 6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride | ROPIVACAINE HYDROCHLORIDE ANHYDROUS | NC00358 | ROPIVACAINE HCl |
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Mecanismo de acción
Sodium channel alpha subunit blocker
Nombres e identificadores Pubchem Sid 488188493 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488188493 Sonrisas canónicas CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.Cl IUPAC Name (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride InChIKey NDNSIBYYUOEUSV-RSAXXLAASA-N INCHI 1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H/t15-;/m0./s1 Isómeros SMILES CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C.Cl PubChem CID 175804 Peso molecular 310.86
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Clase Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent Alpha amino acid amides Alternative Parents Piperidinecarboxamides Anilides m-Xylenes N-arylamides Trialkylamines Secondary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organic oxides Hydrochlorides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents Alpha-amino acid amide - 2-piperidinecarboxamide - Piperidinecarboxamide - Anilide - M-xylene - Xylene - N-arylamide - Monocyclic benzene moiety - Piperidine - Benzenoid - Carboxamide group - Secondary carboxylic acid amide - Tertiary amine - Tertiary aliphatic amine - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Hydrochloride - Amine - Aromatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids. External Descriptors hydrochloride Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solubility (25°C) In vitro DMSO: 62 mg/mL (199.44 mM); Ethanol: 62 mg/mL (199.44 mM); Water: 46 mg/mL (147.97 mM); Sensibilidad Moisture sensitive Peso molecular 310.900 g/mol XLogP3 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 2 Rotatable Bond Count 4 Exact Mass 310.181 Da Monoisotopic Mass 310.181 Da Topological Polar Surface Area 32.299 Ų Heavy Atom Count 21 Formal Charge 0 Complexity 308.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
Citations of This Product Referencias 1. Xiaokang Guan, Qiao Lu, Xiangxu Zhao, Xiaowen Yan, Renato Zenobi. (2023) Spatio-Temporal Analysis of Anesthetics in Mice by Solid-Phase Microextraction: Dielectric Barrier Discharge Ionization Mass Spectrometry. ANALYTICAL CHEMISTRY, [PMID:37560898 ] [10.1021/acs.analchem.3c02123 ] 2. Ce Wu, Di Wu, LiJie Xie, HouYong Yan, Wei Zhang, Fei Yu. (2026) Near-Infrared Responsive Injectable Thermosensitive Hydrogel Sequentially Releases Dexmedetomidine and Ropivacaine for Postoperative Pain Management. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID: [10.1016/j.colsurfa.2026.139503 ]
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