Rp-8-Br-cGMPS - Moligand™, ≥98% , CAS No.150418-07-8

CAS: 150418-07-8 Cat. No.: R275791 Peso molecular: 440.17 PubChem CID: 3035839

GRADE & PURITY Moligand™, ≥98%

Synonyms

DTXSID20933942 | Rp-8-BrcGMPS | (R)-8-Bromoguanosine cyclic 3',5'-(hydrogen phosphorothioate) | O-{[5-(8-Bromo-2-imino-1,2-dihydro-9H-purin-9-yl)-3,4-dihydroxy-2,5-dihydrofuran-2-yl]methyl} dihydrogen phosphorothioate | Rp-8-bromoguanosine 3',5'-cyclic mo

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Sinónimos

DTXSID20933942 | Rp-8-BrcGMPS | (R)-8-Bromoguanosine cyclic 3', 5'-(hydrogen phosphorothioate) | O-{[5-(8-Bromo-2-imino-1, 2-dihydro-9H-purin-9-yl)-3, 4-dihydroxy-2, 5-dihydrofuran-2-yl]methyl} dihydrogen phosphorothioate | Rp-8-bromoguanosine 3', 5'-cyclic mo

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

cGMP blocker. Competitively inhibits relaxation elicited by 8-Br-cGMP in isolated rabbit aorta contracted by phenylephrine at 30 μM.

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: C1=C2C(=NC(=N1)N)N(C(=N2)Br)C3C(=C(C(O3)COP(=S)(O)O)O)O
• IUPAC Name: (2R,5R)-2-(2-amino-8-bromopurin-9-yl)-5-(dihydroxyphosphinothioyloxymethyl)-2,5-dihydrofuran-3,4-diol
• InChIKey: NKBRWLDMUXONRI-SPGJFGJESA-N
• INCHI: 1S/C10H11BrN5O6PS/c11-9-14-3-1-13-10(12)15-7(3)16(9)8-6(18)5(17)4(22-8)2-21-23(19,20)24/h1,4,8,17-18H,2H2,(H2,12,13,15)(H2,19,20,24)/t4-,8-/m1/s1
• Isómeros SMILES: C1=C2C(=NC(=N1)N)N(C(=N2)Br)[C@H]3C(=C([C@H](O3)COP(=S)(O)O)O)O
• PubChem CID: 3035839
• Peso molecular: 440.17

Propiedades químicas y físicas

• Solubilidad: Soluble in water to 50 mM