Determine the necessary mass, volume, or concentration for preparing a solution.
SAE-14 - ≥98% , CAS No.1241280-25-0
Disponible para pedir
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items
Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC 50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC 50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice
In Vitro
SAE-14 (compound SAE-14) can able to antagonize 7α, 25-OHC–induced calcium mobilization with an IC 50 value below 50 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: The human leukemia (HL)-60 cells Concentration: 5×of the antagonist Incubation Time: 15 min Result: Had GPR183-specific (IC 50 : 28.5nM) and abolished 7a, 25-OHC–induced calcium mobilization in the HL-60 cells.
In Vivo
SAE-14 (compound SAE-14) (i.th.; 2.9 µM; once) can reverse nerve injury-induced allodynia in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male and female ICR mice Dosage: 2.9 µM Administration: intrathecal (i.th.) injections; 2.9 µM; once Result: Reversed CCI-induced mechanical allodynia in a time-dependent manner.
Form:Solid
IC50& Target:IC50: 28.5 nM (GPR183)
Specifications
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC 50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC 50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Nombres e identificadores
| Sonrisas canónicas | O=C(NC1=CC(N2CCOCC2)=CC(F)=C1)CCC3=CC=C(F)C(F)=C3 |
|---|---|
| Peso molecular | 364.36 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 100 mg/mL (274.45 mM; ultrasonic and warming and heat to 60°C) |
|---|
Calculadoras de soluciones
Reseñas
Reseñas de cliente
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.