(Sar1)-Angiotensin II - ≥99% , CAS No.51833-69-3

CAS: 51833-69-3 Cat. No.: A651887 Peso molecular: 1002.17 PubChem CID: 122122

GRADE & PURITY ≥99%

Synonyms

1-Sar-5-ile-angiotensin II | angiotensin II, Sar(1)-Ile(5)- | Angiotensin II, 1-(N-methylglycine)-5-L-isoleucine- | (2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-meth

Storage

Protected from light,Argon charged,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a K d of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes .

In Vitro

(Sar1)-Angiotensin II (1 μM/day; 9 d) increases the total protein content in embryonic chick myocytes by 18.5, 26.2, and 22.2% at 5, 7, and 9 days, respectively. (Sar1)-Angiotensin II binds to brain membrane-rich particles in cynomolgus monkey brain, with a K d of 2.7 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Sinónimos

1-Sar-5-ile-angiotensin II | angiotensin II, Sar(1)-Ile(5)- | Angiotensin II, 1-(N-methylglycine)-5-L-isoleucine- | (2S)-2-[[(2S)-1-[(2S)-2-[[(2S, 3S)-2-[[(2S)-2-[[(2S)-2-[[5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-meth

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor . (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a K d of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell gr

Condiciones de almacenamiento de almacenamiento

Protected from light, Argon charged, Desiccated, Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

AGONIST

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC
• IUPAC Name: (2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
• InChIKey: WCYZYYURIHACQW-PEFVFWBQSA-N
• INCHI: 1S/C49H71N13O10/c1-6-29(4)41(46(69)58-36(24-32-25-53-27-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)40(28(2)3)60-42(65)34(56-39(64)26-52-5)14-10-20-54-49(50)51/h7-9,12-13,16-19,25,27-29,34-38,40-41,52,63H,6,10-11,14-15,20-24,26H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,50,51,54)/t29-,34?,35-,36-,37-,38-,40-,41-/m0/s1
• Isómeros SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC
• CAS alternativo: 51833-69-3
• PubChem CID: 122122
• Términos de entrada MeSH: 1-Sar-5-Ile-angiotensin II;angiotensin II, Sar(1)-Ile(5)-;angiotensin II, Sar(1)-Ile(5)-, (5-L-allo-Ile)-isomer;angiotensin II, Sar(1)-Ile(5)-, (7-D-Pro)-isomer;angiotensin II, sarcosyl(1)-isoleucine(5)-;S1-AII
• Peso molecular: 1002.17

Propiedades químicas y físicas

• Solubilidad: H2O Peptide Solubility and Storage Guidelines: 1. Calculate the length of the peptide. 2. Calculate the overall charge of the entire peptide according to the following table: Contents Assign value Acidic amino acid Asp (D), Glu (E), a