Sarakalim , Sulfonylurea receptors; K-ATP channels opener, CAS No.148430-28-8, Sulfonylurea receptors; K-ATP channels opener

CAS: 148430-28-8 Cat. No.: S671076 Peso molecular: 408.4

Synonyms

Sarakalim | 6-trifluoromethyl-2,2-dimethyl-3-(N-hydroxyacetamido)methyl-4-(2-oxo-1,2-dihydropyridin-1-yl)-2H-1-benzopyran | N-((2,2-Dimethyl-4-(2-oxo-1(2H)-pyridyl)-6-(trifluoromethyl)-2H-1-benzopyran-3-yl)methyl)acetohydroxamic acid | UNII-2BY2U8GO3M | C

Storage

Room temperature

Specifications

Sinónimos

Sarakalim | 6-trifluoromethyl-2, 2-dimethyl-3-(N-hydroxyacetamido)methyl-4-(2-oxo-1, 2-dihydropyridin-1-yl)-2H-1-benzopyran | N-((2, 2-Dimethyl-4-(2-oxo-1(2H)-pyridyl)-6-(trifluoromethyl)-2H-1-benzopyran-3-yl)methyl)acetohydroxamic acid | UNII-2BY2U8GO3M | C

Condiciones de almacenamiento de almacenamiento

Room temperature

Tipo de acción

OPENER

Mecanismo de acción

Sulfonylurea receptors; K-ATP channels opener

Propiedades del producto

• ALogP: 1.8

Nombres e identificadores

• Sonrisas canónicas: CC(=O)N(CC1=C(C2=C(C=CC(=C2)C(F)(F)F)OC1(C)C)N3C=CC=CC3=O)O
• IUPAC Name: N-[[2,2-dimethyl-4-(2-oxopyridin-1-yl)-6-(trifluoromethyl)chromen-3-yl]methyl]-N-hydroxyacetamide
• InChIKey: FXRJKZVWFJSKGI-UHFFFAOYSA-N
• INCHI: 1S/C20H19F3N2O4/c1-12(26)25(28)11-15-18(24-9-5-4-6-17(24)27)14-10-13(20(21,22)23)7-8-16(14)29-19(15,2)3/h4-10,28H,11H2,1-3H3
• Isómeros SMILES: CC(=O)N(CC1=C(C2=C(C=CC(=C2)C(F)(F)F)OC1(C)C)N3C=CC=CC3=O)O
• Peso molecular: 408.4
• Reaxy-Rn: 13761749
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13761749&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Benzopyrans
      • Subclass 1-benzopyrans

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Not available
• Direct Parent: 2,2-dimethyl-1-benzopyrans
• Alternative Parents: Pyridinones Alkyl aryl ethers Dihydropyridines Benzenoids Acetamides Acetohydroxamic acids Heteroaromatic compounds Lactams Oxacyclic compounds Azacyclic compounds Organic oxides Organonitrogen compounds Alkyl fluorides Organofluorides Carbonyl compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 2,2-dimethyl-1-benzopyran - Alkyl aryl ether - Dihydropyridine - Pyridinone - Hydropyridine - Pyridine - Benzenoid - Heteroaromatic compound - Acetohydroxamic acid - Acetamide - Hydroxamic acid - Lactam - Carboxylic acid derivative - Ether - Oxacycle - Azacycle - Organohalogen compound - Alkyl halide - Hydrocarbon derivative - Organic oxide - Alkyl fluoride - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 2,2-dimethyl-1-benzopyrans. These are organic compounds containing a 1-benzopyran moiety that carries two methyl groups at the 2-position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y