≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Conservar a -20°C Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Descripción del producto
SCH28080 es un inhibidor reversible, K+-competitivo de la H,K-ATPasa gástrica, con un Ki de 0,12 μM. El SCH28080 es un inhibidor eficaz de la secreción ácida in vivo y con actividad antiúlcera gástrica.
Aplicacióndel producto
El SCH-28080 se utilizó en el tratamiento de embriones de pez cebra para estudiar el papel de la H+/K+-ATPasa en el establecimiento del eje izquierda-derecha durante el desarrollo.
Potente inhibidor de la H+, K+-ATPasa (IC50= 20 nM); se une al sitio de reconocimiento del K+ y es competitivo con respecto al K+. Inhibe la secreción ácida gástrica in vitroe in vivo.
This compound belongs to the class of organic compounds known as imidazopyridines. These are organic polycyclic compounds containing an imidazole ring fused to a pyridine ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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