≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes
In Vitro
SCO-267 (CHO cells) activates the Gα q , Gα s , and Gα 12/13 pathways and β-Arrestin Recruitment. SCO-267 is allosteric with fasiglifam and an endogenous ligand. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
SCO-267 (1 or 10 mg/kg; p.o.) improves insulin sensitivity and exerts sustained glucose-lowering effect . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: N-STZ rats Dosage: 1 or 10 mg/kg Administration: P.o.; Result: Improved insulin sensitivity and exerted sustained glucose-lowering effect.
Form:Solid
IC50& Target:GPR40
| Sonrisas canónicas | CC1=NC(=CC=C1)N(CC(C)(C)C)C(=O)C2=C(C=C(C=C2)OC)N3CCC(CC3)COC4=NC=CC(=C4)C(CC(=O)O)C5CC5 |
|---|---|
| IUPAC Name | (3S)-3-cyclopropyl-3-[2-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]pyridin-4-yl]propanoic acid |
| InChIKey | VVRXREQIOCYUKN-PMERELPUSA-N |
| INCHI | 1S/C36H46N4O5/c1-24-7-6-8-32(38-24)40(23-36(2,3)4)35(43)29-12-11-28(44-5)20-31(29)39-17-14-25(15-18-39)22-45-33-19-27(13-16-37-33)30(21-34(41)42)26-9-10-26/h6-8,11-13,16,19-20,25-26,30H,9-10,14-15,17-18,21-23H2,1-5H3,(H,41,42)/t30-/m0/s1 |
| Isómeros SMILES | CC1=NC(=CC=C1)N(CC(C)(C)C)C(=O)C2=C(C=C(C=C2)OC)N3CCC(CC3)COC4=NC=CC(=C4)[C@@H](CC(=O)O)C5CC5 |
| PubChem CID | 90479828 |
| Términos de entrada MeSH | (3S)-3-cyclopropyl-3-(2-((1-(2-((2,2-dimethylpropyl)(6-methylpyridin-2-yl)carbamoyl)-5-methoxyphenyl)piperidin-4-yl)methoxy)pyridin-4-yl)propanoic acid;SCO-267 |
| Peso molecular | 614.77 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Piperidines |
| Subclass | Phenylpiperidines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpiperidines |
| Alternative Parents | Aminobenzoic acids and derivatives Anthranilamides Aminophenyl ethers Carbocyclic fatty acids Methoxyanilines Anisoles Phenoxy compounds Benzoyl derivatives Dialkylarylamines Methoxybenzenes Alkyl aryl ethers Methylpyridines Imidolactams Heteroaromatic compounds Tertiary carboxylic acid amides Vinylogous amides Amino acids Carboxylic acids Azacyclic compounds Monocarboxylic acids and derivatives Carbonyl compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Phenylpiperidine - Anthranilamide - Aminobenzoic acid or derivatives - Methoxyaniline - Aminophenyl ether - Carbocyclic fatty acid - Benzamide - Benzoic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Anisole - Benzoyl - Methoxybenzene - Phenoxy compound - Aniline or substituted anilines - Phenol ether - Methylpyridine - Alkyl aryl ether - Monocyclic benzene moiety - Fatty acyl - Pyridine - Imidolactam - Benzenoid - Vinylogous amide - Heteroaromatic compound - Tertiary carboxylic acid amide - Amino acid or derivatives - Amino acid - Tertiary amine - Carboxamide group - Azacycle - Monocarboxylic acid or derivatives - Ether - Carboxylic acid - Carboxylic acid derivative - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Amine - Organic oxygen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group. |
| External Descriptors | Not available |
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