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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items (±)-SLV 319 - ≥98% , CAS No.362519-49-1
Synonyms
(+/-)-SLV319(Ibipinabant) | 4-Chloro-N-[1-[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-1-methylamino-meth-(E)-ylidene]-benzenesulfonamide | (E)-3-(4-chlorophenyl)-N-((4-chlorophenyl)sulfonyl)-N'-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxi
Storage
Store at 2-8°C,Argon charged
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general (±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM.
Specifications Sinónimos
(+/-)-SLV319(Ibipinabant) | 4-Chloro-N-[1-[3-(4-chloro-phenyl)-4-phenyl-4, 5-dihydro-pyrazol-1-yl]-1-methylamino-meth-(E)-ylidene]-benzenesulfonamide | (E)-3-(4-chlorophenyl)-N-((4-chlorophenyl)sulfonyl)-N'-methyl-4-phenyl-4, 5-dihydro-1H-pyrazole-1-carboxi
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
High affinity and selective CB1receptor antagonist (Ki= 7.8 nM). Exhibits 1000-fold selectivity for CB1over CB2receptors. InhibitsCP 55, 940-induced hypotension andWIN 55, 212-2-induced hypothermiain vivo. Orally active.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
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Nombres e identificadores Pubchem Sid 488197249 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488197249 Sonrisas canónicas CN=C(NS(=O)(=O)C1=CC=C(C=C1)Cl)N2CC(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4 IUPAC Name 5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide InChIKey AXJQVVLKUYCICH-UHFFFAOYSA-N INCHI 1S/C23H20Cl2N4O2S/c1-26-23(28-32(30,31)20-13-11-19(25)12-14-20)29-15-21(16-5-3-2-4-6-16)22(27-29)17-7-9-18(24)10-8-17/h2-14,21H,15H2,1H3,(H,26,28) Isómeros SMILES CN=C(NS(=O)(=O)C1=CC=C(C=C1)Cl)N2CC(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4 PubChem CID 11179267 Peso molecular 487.4
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Phenylpropanoids and polyketides Clase Stilbenes Subclass Not available Intermediate Tree Nodes Not available Direct Parent Stilbenes Alternative Parents Phenylpyrazoles Benzenesulfonamides Benzenesulfonyl compounds Chlorobenzenes Aryl chlorides Aminosulfonyl compounds Pyrazolines Organosulfonic acids and derivatives Guanidines Azacyclic compounds Propargyl-type 1,3-dipolar organic compounds Hydrocarbon derivatives Organopnictogen compounds Imines Organic oxides Organochlorides Molecular Framework Aromatic heteromonocyclic compounds Substituents Stilbene - Phenylpyrazole - Benzenesulfonamide - Benzenesulfonyl group - Chlorobenzene - Halobenzene - Aryl halide - Monocyclic benzene moiety - Aryl chloride - Benzenoid - Pyrazoline - Aminosulfonyl compound - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Guanidine - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Azacycle - Organic oxygen compound - Organosulfur compound - Organonitrogen compound - Organochloride - Organohalogen compound - Imine - Organic oxide - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Aromatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:DMSO, Max Conc. mg/mL: 48.74, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 4.87, Max Conc. mM: 10 with gentle warming Peso molecular 487.400 g/mol XLogP3 5.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 6 Exact Mass 486.068 Da Monoisotopic Mass 486.068 Da Topological Polar Surface Area 82.500 Ų Heavy Atom Count 32 Formal Charge 0 Complexity 791.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Citations of This Product Referencias 1. Fan Li, Hongli Liu, Xiaojing Wu, Zhicheng Song, Haojia Tang, Maohua Gong, Lei Liu, Fuchang Li. (2023) Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (4): (3123). [PMID:36834536 ] [10.3390/ijms24043123 ]
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