Sovilnesib - Moligand™,≥98% , CAS No.2410796-79-9

CAS: 2410796-79-9 Cat. No.: S651913 Peso molecular: 564.65 PubChem CID: 148163435

GRADE & PURITY Moligand™, ≥98%

Synonyms

AMG 650 | N-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

AMG 650 | N-(2-(4, 4-Difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

Sovilnesib (AMG 650) is a potent, kinesin-like protein KIF18A inhibitor with an IC 50 value of 0.071 μM. Sovilnesib can be used for the research of cancer.

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Pureza

≥98%

Nombres e identificadores

• Isómeros SMILES: CC1=CC(=NC(=N1)N2CCC(CC2)(F)F)NC(=O)C3=C(C=C(C=C3)NS(=O)(=O)CCO)N4CCC5(CC5)CC4
• PubChem CID: 148163435
• Peso molecular: 564.65

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (177.10 mM; Need ultrasonic)
• Sensibilidad: Moisture sensitive
• Peso molecular: 564.600 g/mol
• XLogP3: 3.800
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 8
• Exact Mass: 564.233 Da
• Monoisotopic Mass: 564.233 Da
• Topological Polar Surface Area: 136.000 Ų
• Heavy Atom Count: 39
• Formal Charge: 0
• Complexity: 958.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1