Span™ 60 - ≥99.5% , CAS No.1338-41-6

CAS: 1338-41-6 Cat. No.: S196311 Peso molecular: 430.6 Beilstein Registry Number: 6820761 Número EC: 215-664-9 PubChem CID: 16218600

GRADE & PURITY ≥99.5%

Synonyms

DSSTox_GSID_27396 | EINECS 215-664-9 | MS 33 | Stearic acid, monoester with sorbitan | 1,4-Anhydro-D-glucitol 6-stearate | SCHEMBL5447 | A894695 | Crill 3 | PEONIDIN-3-MONOGLUCOSIDE CHLORIDE | AM803030 | DTXCID6028525 | Estearato de sorbitano | INS-491 |

Storage

Room temperature

Shipped In

Normal

Descripción general

application：

Sorbitan monostearate is used as an emulsifier and as a non-ionic surfactant. It is used in cosmetics, pharmaceuticals and food preparation.

Specifications

Sinónimos

DSSTox_GSID_27396 | EINECS 215-664-9 | MS 33 | Stearic acid, monoester with sorbitan | 1, 4-Anhydro-D-glucitol 6-stearate | SCHEMBL5447 | A894695 | Crill 3 | PEONIDIN-3-MONOGLUCOSIDE CHLORIDE | AM803030 | DTXCID6028525 | Estearato de sorbitano | INS-491 |

Especificaciones y pureza

≥99.5%

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥99.5%

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCCCCCCCCCC(=O)OCC(C1C(C(CO1)O)O)O
• IUPAC Name: [(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] octadecanoate
• InChIKey: HVUMOYIDDBPOLL-XWVZOOPGSA-N
• INCHI: 1S/C24H46O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h20-21,23-26,28H,2-19H2,1H3/t20-,21+,23+,24+/m0/s1
• Isómeros SMILES: CCCCCCCCCCCCCCCCCC(=O)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O
• WGK Alemania: 1
• RTECS: WG2933500
• PubChem CID: 16218600
• Peso molecular: 430.6
• Beilstein: 6820761
• Reaxy-Rn: 5989515

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acid esters

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acid esters
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acid esters
• Alternative Parents: Tetrahydrofurans Secondary alcohols Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Dialkyl ethers Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Fatty acid ester - Tetrahydrofuran - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Oxacycle - Organoheterocyclic compound - Carbonyl group - Organic oxide - Alcohol - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in ethanol (50 mg/ml), isopropanol, mineral oil and vegetable oil. Insoluble in water.
• Punto de inflamación (°C): >149℃
• Punto de fusión (°C): 56-58°C
• Peso molecular: 430.600 g/mol
• XLogP3: 6.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 20
• Exact Mass: 430.329 Da
• Monoisotopic Mass: 430.329 Da
• Topological Polar Surface Area: 96.200 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 417.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Ting Chen, Chaohua Peng, Zhiyong Lin, Guorong Chen, Weiang Luo, Conghui Yuan, Cheng Liu, Yiting Xu, Lizong Dai.  (2023)  Hierarchical structure coating modified cotton fabric with superhydrophobic and flame-retardant performances.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2023.108038]

2. Yang Li, Mingyuan Li, Zhihong Lin, Moris S. Eisen, Dario R. Dekel, Xuezhong He.  (2023)  Boosting CO2/N2 Separation from Cellulose Nanocrystal-Reinforced and Amine-Rich Facilitated Transport Membranes Comprising Deprotonated Amino Acid Salt and Ultrahigh-Molecular-Weight Polyvinylamine.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.3c01566]

3. Xiang Liu, Feng Guo, Desheng Liang, Zilin Li, Yating Cao, Mengqi Chen, Jianjun Xu, Xinliang Liu, Haijun Zhong.  (2023)  Development and evaluation of finasteride niosomes targeting to hair follicles for the management of androgenic alopecia.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2023.104725]

4. Zhiquan Zhang, Baimei Dai, Peng Xu.  (2023)  A Submicron-Scale Plugging Agent for Oil-Based Drilling Fluid Synthesized Using the Inverse Emulsion Polymerization Method.  Polymers,  15  (13): (2815).  [PMID:37447461] [10.3390/polym15132815]

5. Shujuan Yang, Wenqi Qin, Xinyu Zhao, Furui He, Haifang Liu, Qichang Zhou, Junhao Huang, Gaobo Yu, Yuhong Feng, Jiacheng Li.  (2023)  Light-adjusted supramolecular host–guest interfacial recognition for reconfiguring soft colloidal aggregates.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:37167908] [10.1016/j.jcis.2023.04.165]

6. Caining Zhang, Xuman Wang.  (2023)  Study on the Cotton Fabrics with Photoinduced Reversibly Switchable Wettability.  Journal of Nanotechnology,      [PMID:] [10.1155/2023/8422293]

7. Zihao Meng, Jian Wu, Qingyun Li, Youyan Liu, Aixing Tang.  (2023)  Effective immobilization of candida cylindracea lipase on surfactant-modified bentonite.  MOLECULAR CRYSTALS AND LIQUID CRYSTALS,      [PMID:] [10.1080/15421406.2022.2096553]

8. Liya Zeng, Zhe Wang.  (2022)  Development of an environmentally friendly nanoemulsion based on Ginkgo biloba exocarp extracts to control Plutella xylostella.  Micro & Nano Letters,  17  (2): (42-48).  [PMID:] [10.1049/mna2.12104]

9. Ningning Ouyang, Haile Ma, Yanhua Ding, Feng Lu, Lina Guo, Xueli Zhang, Chen Gu.  (2021)  Effect of slit dual-frequency ultrasonic emulsification technology on the stability of walnut emulsions.  ULTRASONICS SONOCHEMISTRY,      [PMID:34942470] [10.1016/j.ultsonch.2021.105876]

10. Mengjie Chang, Simeng Fan, Runqiu Lu, Fei Tao, Facui Yang, Qian Han, Jun Liu, Peng Yang.  (2021)  Suppression of Sunscreen Leakage in Water by Amyloid-like Protein Aggregates.  ACS Applied Materials & Interfaces,      [PMID:34486369] [10.1021/acsami.1c11307]

11. Zhanfeng He, Qiang Chen, Yuanyuan Luo, Yuan He, Yinshan Zhang, Tong Liu, Wenyuan Xu, Jiali Zhang, Yongxin Liu, Leyan Xiong, Shaohui Wang, Zanru Guo.  (2021)  Degradable CO2-responsive microgels with wrinkled porous structure for enhanced, selective and recyclable removal of anionic dyes, Cr(VI) and As(V).  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2021.110374]

12. Xu Ou, Yongyuan Ren, Jiangna Guo, Yingjie Zhou, Yinghui Yuan, Qinbo Liu, Feng Yan.  (2020)  ZIF-8@Poly(ionic liquid)-Grafted Cotton Cloth for Switchable Water/Oil Emulsion Separation.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.0c00495]

13. Yongqiang Zhang, Yingying Cao, Xiangzhan Meng, Chunshan Li, Hui Wang, Suojiang Zhang.  (2020)  Enhancement of transdermal delivery of artemisinin using microemulsion vehicle based on ionic liquid and lidocaine ibuprofen.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:32109824] [10.1016/j.colsurfb.2020.110886]

14. Gang Shao, Junfang Liang, Wanyu Zhao, Biao Zhao, Wen Liu, Hailong Wang, Bingbing Fan, Hongliang Xu, Hongxia Lu, Yiguang Wang, Rui Zhang.  (2019)  Co decorated polymer-derived SiCN ceramic aerogel composites with ultrabroad microwave absorption performance.  JOURNAL OF ALLOYS AND COMPOUNDS,      [PMID:] [10.1016/j.jallcom.2019.152007]

15. Shikang Meng, Lin Sun, Lun Wang, Zibei Lin, Zeyu Liu, Long Xi, Zhenping Wang, Ying Zheng.  (2019)  Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:31306831] [10.1016/j.colsurfb.2019.110352]

16. Hongbin Yang, Leilei Hu, Xuechen Tang, Yongbo Gao, Shuo Shao, Xiangfeng Zhang, Pengxiang Wang, Zhou Zhu, Wanli Kang.  (2018)  Preparation of a fluorescent polymer microsphere and stability evaluation of its profile control system by a fluorescence stability index.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2018.09.019]

17. Umair Azhar, Chuanyong Zong, Xiaozheng Wan, Anhou Xu, Zhang Yabin, Jitao Liu, Shuxiang Zhang, Bing Geng.  (2018)  Methyl Methacrylate HIPE Solely Stabilized by Fluorinated Di-block Copolymer for Fabrication of Highly Porous and Interconnected Polymer Monoliths.  CHEMISTRY-A EUROPEAN JOURNAL,  24  (45): (11619-11626).  [PMID:30003616] [10.1002/chem.201800787]

18. Huina Ruan, Lujing Xu, Shan Hong, Songbai Liu.  (2018)  Highly effective solvent free esterification of phytosterols employing edible metal oxide-emulsifier as catalyst.  CHEMISTRY AND PHYSICS OF LIPIDS,      [PMID:29727623] [10.1016/j.chemphyslip.2018.04.006]

19. Dong-Yang Zhang, Ning Zhang, Peng Song, Jing-Yi Hao, Yi Wan, Xiao-Hui Yao, Tao Chen, Long Li.  (2017)  Functionalized cellulose beads with three dimensional porous structure for rapid adsorption of active constituents from Pyrola incarnata.  CARBOHYDRATE POLYMERS,      [PMID:29254008] [10.1016/j.carbpol.2017.11.111]

20. Daqing Yang, Yige Wang, Yanji Wang, Huanrong Li.  (2016)  A simple and effective luminescence sensor distinguishing cationic surfactants from other type of surfactants.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2016.04.115]

21. Honglai Zhang, Zhaohui Li, Shishun Yu, Qizhen Xiao, Gangtie Lei, Yanhuai Ding.  (2015)  Carbon-encapsulated LiMn2O4 spheres prepared using a polymer microgel reactor for high-power lithium-ion batteries.  JOURNAL OF POWER SOURCES,      [PMID:] [10.1016/j.jpowsour.2015.10.022]

22. Siqi Huan, Long Bai, Guoxiang Liu, Wanli Cheng, Guangping Han.  (2015)  Electrospun nanofibrous composites of polystyrene and cellulose nanocrystals: manufacture and characterization.  RSC Advances,  5  (63): (50756-50766).  [PMID:] [10.1039/C5RA06117B]

23. Songbai Liu, Yuanqing Fu, Si Nian.  (2014)  Buffering colour fluctuation of purple sweet potato anthocyanins to acidity variation by surfactants.  FOOD CHEMISTRY,      [PMID:24874351] [10.1016/j.foodchem.2014.04.029]

24. Hai-Rong Wu, Geng-Lin Li, Guo-Rui Xu, Jia-Wei Chang, Kun-Peng Hou, Wen-Hao Shao, Ji-Rui Hou.  (2024)  Emulsion properties and plugging performances of active crude oil enhanced by amphiphilic Janus nanosheets.  Petroleum Science,      [PMID:] [10.1016/j.petsci.2024.07.026]

25. Onyinyechi Lydia Ugorji, Ikechukwu Virgilius Onyishi, Amarauche Chukwu, Anthony Amaechi Attama.  (2024)  Engineering 5-flourouracil and leucovorin-loaded vesicular systems for possible colon specific delivery: In vitro evaluation and real time cell assay against HCT-116 colon cell lines.  Heliyon,      [PMID:38655322] [10.1016/j.heliyon.2024.e28872]

26. Che Junwen, Zhang Hong, Zeng Jiexiang, Jiang Jianyu, Bai Zijian, Wang Yan, Zhang Fankai.  (2024)  Exploring the fabrication of temperature-regulated spray-bonded cotton using eutectic dual-network phase transition microspheres.  JOURNAL OF POLYMER RESEARCH,  31  (10): (1-12).  [PMID:] [10.1007/s10965-024-04134-w]

27. Mingxin Li, Wensheng Wang, Cong Xu.  (2024)  High-Throughput Synthesis of Superparamagnetic Fe3O4 Nanoparticles in Chaotic Convection Mode.  Chemical Engineering and Processing-Process Intensification,      [PMID:] [10.1016/j.cep.2024.110134]

28. Menghan Li, Jing Yuan, Zhuoni Liu, Tianxiang Yin, Changjun Peng.  (2024)  Multifunctional Deep Eutectic Solvent-Based Microemulsion for Transdermal Delivery of Artemisinin.  LANGMUIR,      [PMID:38412279] [10.1021/acs.langmuir.3c02748]

29. Dan Wang, Yan Wang, Changjiang Li, Junmin Ji.  (2024)  Safe and targeted detoxification of aflatoxins from contaminated peanut oil by palygorskite infiltrated with Span series surfactant.  APPLIED CLAY SCIENCE,      [PMID:] [10.1016/j.clay.2024.107660]

30. Wanping Zhang, Xuefang Shi, Shilian Zheng.  (2024)  Study on Influencing Factors of Nicotinamide Transdermal Absorption In Vitro and the Establishment of an Evaluation Method.  Processes,  12  (1): (202).  [PMID:] [10.3390/pr12010202]

31. Ruoning Zhang, Yanhui Zhang, Tingnan Song, Song Miao, Yanxiang Gao, Like Mao.  (2025)  Shear-responsive oleogels with improved lubrication in oral conditions.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.167053]

32. Zhiyi Zang, Yongkang Wang, Wei Liu, Congcong Chao, Guanghui Cui, Shaojun Wu, Zhanpeng Wu.  (2025)  Amphiphilic Polyphosphazene-Stabilized High Internal Phase Emulsions toward Porous Polymers with Designed Hydrophilicity and Hydrophobicity for Selective Adsorption of Water and Oil.  LANGMUIR,      [PMID:40990335] [10.1021/acs.langmuir.5c02759]

33. Baihong Yu, Yan Shen, Leize Li, Junjing Fan, Jinghao Qu, Jiujun Xu.  (2025)  Ultra-low friction with SiO2 nanoparticles bonded sorbitan monostearate oleogel as green lubricant additives.  TRIBOLOGY INTERNATIONAL,      [PMID:] [10.1016/j.triboint.2025.111032]

34. Shang-Yuan Cheng, Chen-Peng Zhang, Meng-na Chao, Shu-Wei Guo, Gui-Sheng Qi.  (2025)  Development of nanoemulsion CO2 absorbents in an impinging stream rotating packed bed reactor.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.116543]

35. Wenliang Wang, Xiaoxiao Ren, Yong Cui, Yanyi Xue, Bailiang Xue, Xinping Li.  (2025)  Inorganic clay-enhanced cellulose-based superabsorbent composites on swelling performance and responsive behavior.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2025.121049]

36. Zhen Cheng, WenQi Wang, XiuMei Tai, Tao Geng.  (2025)  Study on the formation and stabilization of natural wax emulsions.  JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY,      [PMID:] [10.1080/01932691.2024.2378990]

37. Linghua Zhang, Shu Yang, Ahmed S.M. Saleh, Rui Wang, Zhigang Xiao.  (2025)  Influence of Emulsifier Type on Sunflower Oil Oleogels Structured with Ethylcellulose.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.118841]