Spermine tetrahydrochloride - Moligand™, UltraBio™, Suitable for molecular biology, ≥99.5%(AT) , CAS No.306-67-2

CAS: 306-67-2 Cat. No.: S755716 Peso molecular: 348.18 Número EC: 206-189-8 PubChem CID: 9384

GRADE & PURITY Suitable for molecular biology, Moligand™, UltraBio™, ≥99.5%(AT)

Synonyms

N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride | N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) Tetrahydrochloride

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Descripción general

Used to precipitate DNA from low salt aqueous buffers.

Specifications

Sinónimos

N, N'-Bis(3-aminopropyl)-1, 4-butanediamine Tetrahydrochloride | N1, N1'-(Butane-1, 4-diyl)bis(propane-1, 3-diamine) Tetrahydrochloride

Especificaciones y pureza

Moligand™, UltraBio™, Suitable for molecular biology, ≥99.5%(AT)

Mecanismos bioquímicos y fisiológicos

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™, Suitable for molecular biology, UltraBio™

Pureza

≥99.5%(AT)

Nombres e identificadores

• PH: 4.5-7.0 (25 °C, 1 M in H 2 O)
• Sonrisas canónicas: C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl
• IUPAC Name: N,N'-bis(3-aminopropyl)butane-1,4-diamine;tetrahydrochloride
• InChIKey: XLDKUDAXZWHPFH-UHFFFAOYSA-N
• INCHI: 1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
• Isómeros SMILES: C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl
• WGK Alemania: 3
• RTECS: EJ7230000
• CAS alternativo: 1255099-40-1
• PubChem CID: 9384
• Peso molecular: 348.18
• Reaxy-Rn: 3911771

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Clase Organonitrogen compounds
      • Subclass Amines
        • Level5 Secondary amines
          • Level6 Dialkylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Clase: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Secondary amines
• Direct Parent: Dialkylamines
• Alternative Parents: Organopnictogen compounds Monoalkylamines Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Primary amine - Primary aliphatic amine - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: H 2 O: 1 m at 20 °C, clear, colorless to almost colorless
• Sensibilidad: Moisture sensitive；air sensitive
• Punto de fusión (°C): 315°C
• Peso molecular: 348.200 g/mol
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 11
• Exact Mass: 348.12 Da
• Monoisotopic Mass: 346.122 Da
• Topological Polar Surface Area: 76.100 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 86.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 5

XLogP3

Referencias

1. Shijin Xiong, Xiaoyan Xu, Qiaozhen Liu, Yazhou Xu, Hongbing Ren, Tao Xiong, Mingyong Xie.  (2023)  Integrated metatranscriptomics and metabolomics revealed the metabolic pathways of biogenic amines during Laotan Suancai fermentation.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2023.103517]

2. Yu Wang, Xueping Kong, Fei Li, Bao Li, Lixin Wu, Kai Chen, Yuqing Wu.  (2022)  Mo154 Synergistically Enhanced Antibiofilm and Antibacterial Effects of Spermine via Coassembly.  ACS Applied Bio Materials,      [PMID:36264761] [10.1021/acsabm.2c00692]

3. Yanan Liu, Yuhao Huang, Qileng Aori, Yu Wang, Sai Zhao, Zhen-Lin Xu.  (2026)  A sustained-release antibacterial gelatin hydrogel based on metal-phenolic networks for long-term preservation of prefabricated meat.  FOOD CHEMISTRY,      [PMID:] [10.1016/j.foodchem.2026.149080]