SPT Imidazopyridine 1 - ≥98% , CAS No.1933533-18-6

CAS: 1933533-18-6 Cat. No.: S288862 Peso molecular: 364.44 PubChem CID: 131954583
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid | SPT-IN-1 | Imidazopyridine 1 | SPT Inhibitor 1 | SPT IN 1
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
S288862-1mg
3
199,90US$
5mg
S288862-5mg
3
479,90US$
10mg
S288862-10mg
3
739,90US$
25mg
S288862-25mg
3
1.199,90US$
50mg
S288862-50mg
2
1.799,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Product description:

Potent serine palmitoyl transferase inhibitor

Specifications

Sinónimos
4-[6-(1-Oxoheptyl)imidazo[1, 2-a]pyridin-8-yl]benzeneacetic acid | SPT-IN-1 | Imidazopyridine 1 | SPT Inhibitor 1 | SPT IN 1
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Potent serine palmitoyl transferase (SPT) inhibitor (IC50= 5 nM). Dose-dependently inhibits incorporation of14C-serine into ceramide. Reduces plasma ceramide levelsin vivo. Also increases plasma HDL and reduces vLDL cholesterol levels in rats.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasCCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O
IUPAC Name2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid
InChIKeyMMYRYMMKMUTPBB-UHFFFAOYSA-N
INCHI1S/C22H24N2O3/c1-2-3-4-5-6-20(25)18-14-19(22-23-11-12-24(22)15-18)17-9-7-16(8-10-17)13-21(26)27/h7-12,14-15H,2-6,13H2,1H3,(H,26,27)
Isómeros SMILES CCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O
PubChem CID 131954583
Peso molecular 364.44

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
SPTLC1 Tchem Serine palmitoyltransferase 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Objetivos asociados (no humanos)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeFechaArticulo
C2425493Certificate of AnalysisMar 11, 2024 S288862
C2425494Certificate of AnalysisMar 11, 2024 S288862
C2425495Certificate of AnalysisMar 11, 2024 S288862
C2425496Certificate of AnalysisMar 11, 2024 S288862
C2425497Certificate of AnalysisMar 11, 2024 S288862
C2425505Certificate of AnalysisMar 11, 2024 S288862
C2425506Certificate of AnalysisMar 11, 2024 S288862
C2425507Certificate of AnalysisMar 11, 2024 S288862
C2425508Certificate of AnalysisMar 11, 2024 S288862
C2425509Certificate of AnalysisMar 11, 2024 S288862
Propiedades químicas y físicas
SolubilidadSolvent:DMSO, Max Conc. mg/mL: 36.44, Max Conc. mM: 100
Peso molecular364.400 g/mol
XLogP35.000
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count9
Exact Mass364.179 Da
Monoisotopic Mass364.179 Da
Topological Polar Surface Area71.700 Ų
Heavy Atom Count27
Formal Charge0
Complexity502.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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