SR-318 - Moligand™, 10mM in DMSO , CAS No.2413286-32-3

CAS: 2413286-32-3 Cat. No.: S655951 Peso molecular: 459.58 PubChem CID: 139030333
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Estado
Price
Qty
1ml
S655951-1ml
1
110,90US$
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

SR-318 is a potent and highly selective p38 MAPK inhibitor with IC 50 s of 5 nM, 32 nM and 6.11 μM for p38α , p38β and p38α/β, respectively. SR-318 potently inhibits the TNF-α release in whole blood with an IC 50 of 283 nM. SR-318 has anti-cancer and anti-inflammatory activity

In Vitro

SR-318 presents a potent and selective type-II inhibitor of p38α/β that can be used as a chemical probe for targeting this particular inactive state of these two p38 isoforms. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:p38α 5 nM (IC 50 ) p38β 32 nM (IC 50 )

Specifications

Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
SR-318 is a potent and highly selective p38 MAPK inhibitor with IC 50 s of 5 nM, 32 nM and 6.11 μM for p38α , p38β and p38α/β, respectively. SR-318 potently inhibits the TNF-α release in whole blood with an IC 50 of 283 nM. SR-318 has anti-cancer and anti
Condiciones de almacenamiento de almacenamiento
Protected from light, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Nombres e identificadores
Isómeros SMILES C1CCC(CC1)CCCNC(=O)C2=CC=C(C=C2)CNC(=O)C3=C(N(N=C3)C4=CC=CC=C4)N
PubChem CID 139030333
Términos de entrada MeSH 5-Amino-N-(4-((3-cyclohexylpropyl)carbamoyl)benzyl)-1-phenyl-1H-pyrazole-4-carboxamide;SR-318
Peso molecular 459.58

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
MAPK11 Tchem Mitogen-activated protein kinase 11 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAPK14 Tchem Mitogen-activated protein kinase 14 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Sensibilidadlight sensitive
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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